中国药物应用与监测
中國藥物應用與鑑測
중국약물응용여감측
CHINESE JOURNAL OF DRUG APPLICATION AND MONITORING
2014年
3期
189-190
,共2页
甘露聚糖肽注射液%过敏性休克%药品不良反应
甘露聚糖肽註射液%過敏性休剋%藥品不良反應
감로취당태주사액%과민성휴극%약품불량반응
Mannatide injection%Allergic shock%Adverse drug reaction
1例54岁女性患者，既往无食物、药物过敏史，因膜性肾病Ⅰ期8个月给予甘露聚糖肽注射液。用药2 min后，患者出现呼吸困难、胸闷、憋气等症状，HR 90次·min-1，氧饱和度92%，BP 116/69 mm Hg，吸气时可闻及明显喘鸣音，面部及球结膜充血，双前臂皮肤色红，无皮疹。立即停止输入，更换输液器，并给予吸氧，抗过敏及扩充血容量治疗。40 min后，患者上述症状缓解，皮肤颜色正常，面部及球结膜充血消失。
1例54歲女性患者，既往無食物、藥物過敏史，因膜性腎病Ⅰ期8箇月給予甘露聚糖肽註射液。用藥2 min後，患者齣現呼吸睏難、胸悶、憋氣等癥狀，HR 90次·min-1，氧飽和度92%，BP 116/69 mm Hg，吸氣時可聞及明顯喘鳴音，麵部及毬結膜充血，雙前臂皮膚色紅，無皮疹。立即停止輸入，更換輸液器，併給予吸氧，抗過敏及擴充血容量治療。40 min後，患者上述癥狀緩解，皮膚顏色正常，麵部及毬結膜充血消失。
1례54세녀성환자，기왕무식물、약물과민사，인막성신병Ⅰ기8개월급여감로취당태주사액。용약2 min후，환자출현호흡곤난、흉민、별기등증상，HR 90차·min-1，양포화도92%，BP 116/69 mm Hg，흡기시가문급명현천명음，면부급구결막충혈，쌍전비피부색홍，무피진。립즉정지수입，경환수액기，병급여흡양，항과민급확충혈용량치료。40 min후，환자상술증상완해，피부안색정상，면부급구결막충혈소실。
One 54-year-old female patient without allergic history of food and drug was diagnosed as stage I membranous nephropathy. Mannatide injection was given to the patient. Two minutes later, the patient presented with dyspnea, chest congestion, breathlessness with HR of 90 bites per minute, SpO2 of 92%, BP of 116/69 mm Hg. Clearly wheezing when inhaling, congestion of face and bulbar conjunctiva, red skin in arms without rash were observed. So the medicine was immediately stopped, infusion apparatus were replaced, the inhalation of oxygen, anti-allergic therapy and the rescue of blood volume expansion were given. Forty minutes later, the symptoms alleviated, the colour of skin was normal, the hyperemia of face and bulbar conjunctiva disappeared.
