CAJ | 학술논문

目的：观察尼麦角林对治疗慢性脑供血不足的临床疗效。方法160例慢性脑供血不足患者随机分为治疗组和对照组。治疗组在基础治疗的同时,给予尼麦角林10 mg,口服,3次/日；对照组给予尼莫地平20 mg,口服,3次/日,疗程1个月。观察临床有效率及经颅彩色多谱勒超声（ TCD)检查的结果在治疗前后2组之间的变化。结果治疗组临床有效率及TCD指标改善情况均优于对照组,2组间差异具有统计学意义。结论尼麦角林治疗慢性脑供血不足安全可靠。
목적：관찰니맥각림대치료만성뇌공혈불족적림상료효。방법160례만성뇌공혈불족환자수궤분위치료조화대조조。치료조재기출치료적동시,급여니맥각림10 mg,구복,3차/일；대조조급여니막지평20 mg,구복,3차/일,료정1개월。관찰림상유효솔급경로채색다보륵초성（ TCD)검사적결과재치료전후2조지간적변화。결과치료조림상유효솔급TCD지표개선정황균우우대조조,2조간차이구유통계학의의。결론니맥각림치료만성뇌공혈불족안전가고。
Objective To observe the curative effect of nicergoline in the treatment of chronic cerebral circulation insufficiency ( CC-CI) . Methods 160 cases with CCCI were randomly divided into the treatment group which were administered 10 mg of oral Nicergoline, three times per day for one month,and the control group which were given 20 mg of oral nimodipine,three times per day for one month. The clinical effective rate and the transcranial Doppler ultrasound ( TCD) between the two groups before and after treatment were observed. Results There were significant difference in clinical effective rate and TCD index assessment between the two groups(P<0. 05). Conclu-sion Nicergoline is an effective and safe treatment for chronic cerebral circulation insufficiency.