中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2014年
3期
495-497,503
,共4页
医院感染%菌群分布%耐药监测%抗菌药物
醫院感染%菌群分佈%耐藥鑑測%抗菌藥物
의원감염%균군분포%내약감측%항균약물
hospital infection%distribution of pathogen%drug resistance monitoring%antimicrobial drugs
目的：对送检标本中分离的致病菌分布及耐药趋势进行分析，旨在做好防控措施和指导临床合理使用抗菌药物。方法进行常规培养分离鉴定，药敏试验应用K-B纸片扩散法，按CLSI/NCCLS规定的标准进行。结果3年共分离到1071株细菌，其中G＋菌414株，占38．65％，G-菌465株，占43．41％。 MRSA检出率明显上升，分别为：3％、9％、13％。纳入目标性监测的多重耐药菌（MDRO）包括：耐甲氧西林金黄色葡萄球菌（MRSA）20株、多重耐药的大肠埃希菌25株、多重耐药的肺炎克雷伯菌4株、耐万古霉素肠球菌（ VRE）1株、多重耐药的铜绿假单胞菌1株。2013年金黄色葡萄球菌开始出现万古霉素耐药株，耐药率为16％。结论妇幼专科医院病原菌群相比综合医院病种少，病原菌也相对较少，但是病原菌群也同样随着时间推移在不断变迁，耐药性逐年增长，加强监测防控，指导临床合理用药也很有意义。
目的：對送檢標本中分離的緻病菌分佈及耐藥趨勢進行分析，旨在做好防控措施和指導臨床閤理使用抗菌藥物。方法進行常規培養分離鑒定，藥敏試驗應用K-B紙片擴散法，按CLSI/NCCLS規定的標準進行。結果3年共分離到1071株細菌，其中G＋菌414株，佔38．65％，G-菌465株，佔43．41％。 MRSA檢齣率明顯上升，分彆為：3％、9％、13％。納入目標性鑑測的多重耐藥菌（MDRO）包括：耐甲氧西林金黃色葡萄毬菌（MRSA）20株、多重耐藥的大腸埃希菌25株、多重耐藥的肺炎剋雷伯菌4株、耐萬古黴素腸毬菌（ VRE）1株、多重耐藥的銅綠假單胞菌1株。2013年金黃色葡萄毬菌開始齣現萬古黴素耐藥株，耐藥率為16％。結論婦幼專科醫院病原菌群相比綜閤醫院病種少，病原菌也相對較少，但是病原菌群也同樣隨著時間推移在不斷變遷，耐藥性逐年增長，加彊鑑測防控，指導臨床閤理用藥也很有意義。
목적：대송검표본중분리적치병균분포급내약추세진행분석，지재주호방공조시화지도림상합리사용항균약물。방법진행상규배양분리감정，약민시험응용K-B지편확산법，안CLSI/NCCLS규정적표준진행。결과3년공분리도1071주세균，기중G＋균414주，점38．65％，G-균465주，점43．41％。 MRSA검출솔명현상승，분별위：3％、9％、13％。납입목표성감측적다중내약균（MDRO）포괄：내갑양서림금황색포도구균（MRSA）20주、다중내약적대장애희균25주、다중내약적폐염극뢰백균4주、내만고매소장구균（ VRE）1주、다중내약적동록가단포균1주。2013년금황색포도구균개시출현만고매소내약주，내약솔위16％。결론부유전과의원병원균군상비종합의원병충소，병원균야상대교소，단시병원균군야동양수착시간추이재불단변천，내약성축년증장，가강감측방공，지도림상합리용약야흔유의의。
Objective To analyze the distribution of pathogenic bacteria isolated from specimens and the drug resistance tendency , so as to make prevention and control and guide rational use of antimicrobial drugs .Methods Conventional culture isolation , identification and susceptibility testing were done with K-B disk diffusion method according to standard CLSI /NCCLS requirement .Results In these three years totally 1 071 bacteria were isolated, including 414 G+strains (38.65%) and 465 G-strains (43.41%).The positive rate of MRSA increased significantly , and they were 3%, 9%and 13%, respectively .The multiple resistant bacteria ( MDRO) with targeted monitoring included methicillin-resistant staphylococcus aureus (MRSA, 20 strains), multi-drug resistant Escherichia coli (25 strains), multi-drug resistant klebsiella pneumoniae ( 4 strains ) , vancomycin-resistant enterococci ( VRE, 1 strain ) and multi-drug resistant pseudomonas aeruginosa aeromonas ( 1 strain ) .In 2013 vancomycin resistant strains were found in staphylococcus aureus , and the resistant rate was 16%.Conclusion Compared with comprehensive hospitals , the pathogen groups and pathogens are less in maternal and child hospitals . However, the pathogen groups constantly change over time and drug resistance grows year after year .Strengthening monitoring and prevention to guide rational drug use in clinics is also important .
