医学临床研究
醫學臨床研究
의학림상연구
JOURNAL OF CLINICAL RESEARCH
2014年
5期
970-971,974
,共3页
邵芬%李晓行%章臻翊%罗亚衡
邵芬%李曉行%章臻翊%囉亞衡
소분%리효행%장진익%라아형
糖尿病,2 型/并发症%卒中%超声检查%糖尿病视网膜病变
糖尿病,2 型/併髮癥%卒中%超聲檢查%糖尿病視網膜病變
당뇨병,2 형/병발증%졸중%초성검사%당뇨병시망막병변
Diabetes Mellitus,Type 2/CO%Stroke%Ultrasonography%Diabetic Retinopathy
【目的】探讨老年2型糖尿病(T2DM)并发缺血性脑卒中与颈动脉狭窄及视网膜病变程度的相关性。【方法】老年T2DM 患者161例,并发脑卒中58例(脑卒中组),非脑卒中103例(非脑卒中组)。超声检测两组患者颈动脉内膜中层厚度(IMT),并行眼底检查。【结果】两组患者颈动脉粥样硬化斑块发生部位多见于颈总动脉近分叉处,脑卒中组颈动脉不稳定性斑块的检出率、颈动脉 IMT值显著高于非脑卒中组(P<0.05),且脑卒中组单纯型糖尿病视网膜病变(NPDR)及增殖型糖尿病视网膜病变(PDR)患者 IMT值、颈动脉不稳定斑块数检出率均显著高于非脑卒中组(P<0.05);相关性分析显示 IMT与眼底病变程度显著相关(r=0.5509,P <0.05)。【结论】颈动脉 IMT和视网膜病变程度与老年T2DM并发缺血性脑卒中存在相关性。
【目的】探討老年2型糖尿病(T2DM)併髮缺血性腦卒中與頸動脈狹窄及視網膜病變程度的相關性。【方法】老年T2DM 患者161例,併髮腦卒中58例(腦卒中組),非腦卒中103例(非腦卒中組)。超聲檢測兩組患者頸動脈內膜中層厚度(IMT),併行眼底檢查。【結果】兩組患者頸動脈粥樣硬化斑塊髮生部位多見于頸總動脈近分扠處,腦卒中組頸動脈不穩定性斑塊的檢齣率、頸動脈 IMT值顯著高于非腦卒中組(P<0.05),且腦卒中組單純型糖尿病視網膜病變(NPDR)及增殖型糖尿病視網膜病變(PDR)患者 IMT值、頸動脈不穩定斑塊數檢齣率均顯著高于非腦卒中組(P<0.05);相關性分析顯示 IMT與眼底病變程度顯著相關(r=0.5509,P <0.05)。【結論】頸動脈 IMT和視網膜病變程度與老年T2DM併髮缺血性腦卒中存在相關性。
【목적】탐토노년2형당뇨병(T2DM)병발결혈성뇌졸중여경동맥협착급시망막병변정도적상관성。【방법】노년T2DM 환자161례,병발뇌졸중58례(뇌졸중조),비뇌졸중103례(비뇌졸중조)。초성검측량조환자경동맥내막중층후도(IMT),병행안저검사。【결과】량조환자경동맥죽양경화반괴발생부위다견우경총동맥근분차처,뇌졸중조경동맥불은정성반괴적검출솔、경동맥 IMT치현저고우비뇌졸중조(P<0.05),차뇌졸중조단순형당뇨병시망막병변(NPDR)급증식형당뇨병시망막병변(PDR)환자 IMT치、경동맥불은정반괴수검출솔균현저고우비뇌졸중조(P<0.05);상관성분석현시 IMT여안저병변정도현저상관(r=0.5509,P <0.05)。【결론】경동맥 IMT화시망막병변정도여노년T2DM병발결혈성뇌졸중존재상관성。
[Objective]To explore the correlation of complicated ischemic stroke with the degree of carotid stenosis and retinopathy in elderly patients with type 2 diabetes mellitus(T2DM).[Methods]Among 161 elderly patients with T2DM,58 patients were complicated with stroke(stroke group)and 103 patients were not complicated with stroke(non-stroke group).Carotid intima-media thickness(IMT)of patients in 2 groups was detected by ultrasonography.Fundus examination was performed in all patients.[Results]Carotid atherosclerotic plaques of patients in 2 groups mainly oc-curred at the site near the bifurcation of common carotid artery.The detection rate of instable carotid plaque and carotid IMT in stroke group were significantly higher than those in non-stroke group(P<0.05).Carotid IMT of patient with simple diabetic retinopathy(NPDR)and proliferative diabetic retinopathy(PDR)in stroke group was significantly higher than that in non-stroke group(P<0.05).Correlation analysis showed that IMT was significantly associated with fundus lesion(r=0.5509,P<0.05).[Conclusion]Carotid IMT and the degree of retinopathy are related with complicated is-chemic stroke in elderly patients with TDM.