CAJ | 학술논문

【目的】探讨老年2型糖尿病（T2DM）并发缺血性脑卒中与颈动脉狭窄及视网膜病变程度的相关性。【方法】老年T2DM 患者161例，并发脑卒中58例（脑卒中组），非脑卒中103例（非脑卒中组）。超声检测两组患者颈动脉内膜中层厚度（IMT），并行眼底检查。【结果】两组患者颈动脉粥样硬化斑块发生部位多见于颈总动脉近分叉处，脑卒中组颈动脉不稳定性斑块的检出率、颈动脉 IMT值显著高于非脑卒中组（P＜0．05），且脑卒中组单纯型糖尿病视网膜病变（NPDR）及增殖型糖尿病视网膜病变（PDR）患者 IMT值、颈动脉不稳定斑块数检出率均显著高于非脑卒中组（P＜0．05）；相关性分析显示 IMT与眼底病变程度显著相关（r＝0．5509，P ＜0．05）。【结论】颈动脉 IMT和视网膜病变程度与老年T2DM并发缺血性脑卒中存在相关性。
【목적】탐토노년2형당뇨병（T2DM）병발결혈성뇌졸중여경동맥협착급시망막병변정도적상관성。【방법】노년T2DM 환자161례，병발뇌졸중58례（뇌졸중조），비뇌졸중103례（비뇌졸중조）。초성검측량조환자경동맥내막중층후도（IMT），병행안저검사。【결과】량조환자경동맥죽양경화반괴발생부위다견우경총동맥근분차처，뇌졸중조경동맥불은정성반괴적검출솔、경동맥 IMT치현저고우비뇌졸중조（P＜0．05），차뇌졸중조단순형당뇨병시망막병변（NPDR）급증식형당뇨병시망막병변（PDR）환자 IMT치、경동맥불은정반괴수검출솔균현저고우비뇌졸중조（P＜0．05）；상관성분석현시 IMT여안저병변정도현저상관（r＝0．5509，P ＜0．05）。【결론】경동맥 IMT화시망막병변정도여노년T2DM병발결혈성뇌졸중존재상관성。
[Objective]To explore the correlation of complicated ischemic stroke with the degree of carotid stenosis and retinopathy in elderly patients with type 2 diabetes mellitus(T2DM).[Methods]Among 161 elderly patients with T2DM,58 patients were complicated with stroke(stroke group)and 103 patients were not complicated with stroke(non-stroke group).Carotid intima-media thickness(IMT)of patients in 2 groups was detected by ultrasonography.Fundus examination was performed in all patients.[Results]Carotid atherosclerotic plaques of patients in 2 groups mainly oc-curred at the site near the bifurcation of common carotid artery.The detection rate of instable carotid plaque and carotid IMT in stroke group were significantly higher than those in non-stroke group(P<0.05).Carotid IMT of patient with simple diabetic retinopathy(NPDR)and proliferative diabetic retinopathy(PDR)in stroke group was significantly higher than that in non-stroke group(P<0.05).Correlation analysis showed that IMT was significantly associated with fundus lesion(r=0.5509,P<0.05).[Conclusion]Carotid IMT and the degree of retinopathy are related with complicated is-chemic stroke in elderly patients with TDM.