CAJ | 학술논문

【目的】探讨308 nm 准分子激光与窄谱中波紫外线（NB-UVB）局部照射治疗白癜风的疗效。【方法】选择局限型白癜风患者63例，白斑皮损68片，其中36片采用308 nm准分子激光（激光组），32片皮损采用 NB-UVB局部照射治疗（NB-UVB组），2次/周，连续照射30次，比较两组有效率、复色率和不良反应。【结果】激光组复色率、总有效率分别为88．89％、66．67％显著高于 NB-UVB组（68．75％、40．63％），其差异有统计学意义（P＜0．05）；两组患者在治疗过程中，均未出现过严重的不良反应。【结论】308 nm准分子激光治疗白癜风具有疗效好，见效快及安全性高的优势。
【목적】탐토308 nm 준분자격광여착보중파자외선（NB-UVB）국부조사치료백전풍적료효。【방법】선택국한형백전풍환자63례，백반피손68편，기중36편채용308 nm준분자격광（격광조），32편피손채용 NB-UVB국부조사치료（NB-UVB조），2차/주，련속조사30차，비교량조유효솔、복색솔화불량반응。【결과】격광조복색솔、총유효솔분별위88．89％、66．67％현저고우 NB-UVB조（68．75％、40．63％），기차이유통계학의의（P＜0．05）；량조환자재치료과정중，균미출현과엄중적불량반응。【결론】308 nm준분자격광치료백전풍구유료효호，견효쾌급안전성고적우세。
[Objective]To explore the efficacy of 308nm excimer laser vs.narrow-spectrum midrange ultra-violet beam(NB-UVB)for the treatment of vitiligo.[Methods]Totally 63 patients(68 patches of skin lesion) with limited vitiligo were selected.Among them,36 patches were treated with 308nm excimer laser(laser group)and 32 patches were treated with NB-UVB twice a week for continuous 30 times(NB-UVB group). The effective rate,repigmentation rate and adverse reaction were compared between two groups.[Results]The repigmentation rate and total effective rate in laser group were 88.89% and 66.67% respectively,which were markedly higher than those in NB-UVB group(68.75% and 40.63%,respectively),and there was significant difference(P<0.05).No severe adverse reaction was found in two groups during the therapy.[Conclusion]The 308nm excimer laser for the treatment of vitiligo has good efficacy and advantages such as rapid effect and high safety.