CAJ | 학술논문

【目的】分析糖尿病足感染（DFI）病原菌分布情况及耐药情况，为合理选用抗菌药物提供依据。【方法】回顾性分析2011年1月至2013年6月本院收治的96例 DFI患者的病原菌培养及药敏资料。【结果】96例 DFI患者共培养出病原菌134株，其中革兰阳性（G＋）球菌74株（55．2％）、革兰阴性（G-）杆菌55株（41．0％）、真菌5株（3．7％）。G-球菌主要有金黄色葡萄球菌、表皮葡萄球菌、肠球菌，G-杆菌则主要包括大肠埃希菌、肺炎克雷伯杆菌、铜绿假单胞菌。其中，G＋球菌对克拉霉素及红霉素耐药情况严重。G-杆菌中铜绿假单胞菌对多种抗生素耐药严重。【结论】DFI患者应及早、多次的行病原学检查，合理选用抗生素，才能有效控制感染。
【목적】분석당뇨병족감염（DFI）병원균분포정황급내약정황，위합리선용항균약물제공의거。【방법】회고성분석2011년1월지2013년6월본원수치적96례 DFI환자적병원균배양급약민자료。【결과】96례 DFI환자공배양출병원균134주，기중혁란양성（G＋）구균74주（55．2％）、혁란음성（G-）간균55주（41．0％）、진균5주（3．7％）。G-구균주요유금황색포도구균、표피포도구균、장구균，G-간균칙주요포괄대장애희균、폐염극뢰백간균、동록가단포균。기중，G＋구균대극랍매소급홍매소내약정황엄중。G-간균중동록가단포균대다충항생소내약엄중。【결론】DFI환자응급조、다차적행병원학검사，합리선용항생소，재능유효공제감염。
[Objective]To analyze the distribution and drug resistance of pathogenic bacteria in diabetic foot infection in order to provide a basis for reasonable application of antibiotics.[Methods]The data of pathogenic bacteria culture and drug sensitivity of 96 patients with diabetic foot infection in our hospital from Jan.2011 to June 2013 were analyzed retro-spectively.[Results]The 134 strains of pathogenic bacteria in 96 patients with diabetic foot infection were isolated.A-mong them,74 strains were Gram-positive bacteria(55.2%),and 55 strains were Gram-negative bacteria(41.0%),and 5 strains were fungi(3.7%).Common positive coccobacteria were staphylococcus aureus,staphylococcus epidermidis and enterococcus faecalis,while common negative bacteria were Escherichia coli,Klebsiella pneumoniae and pseudomonas aeruginosa.Positive coccobacteria were severely resistant to clarithromycin and erythromycin,while pseudomonas aerugi-nosa in negative bacteria were severely resistant to multiple antibiotics.[Conclusion]For patients with diabetic foot infec-tion,early and multiple etiological examination should be taken.Reasonable selection of antibiotics can control diabetic foot infection effectively.