中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
6期
711-713,722
,共4页
骨质疏松%雌激素%血瘀%血管内皮功能
骨質疏鬆%雌激素%血瘀%血管內皮功能
골질소송%자격소%혈어%혈관내피공능
Osteoporosis%Estrogen%Blood stasis%Vascular endothelial function
血瘀与骨质疏松关系密切。血瘀证病理变化的现代物质基础研究是当今研究的一个热点。研究表明血管内皮相关因子与血瘀的形成关系密切，雌激素通过促进NO、PGI2等血管舒张活性因子的表达，抑制ET、Ang Ⅱ、TXA2等血管收缩因子表达而对血瘀证病理变化有一定影响。雌激素可能通过改善血瘀而影响骨质疏松的发生。
血瘀與骨質疏鬆關繫密切。血瘀證病理變化的現代物質基礎研究是噹今研究的一箇熱點。研究錶明血管內皮相關因子與血瘀的形成關繫密切，雌激素通過促進NO、PGI2等血管舒張活性因子的錶達，抑製ET、Ang Ⅱ、TXA2等血管收縮因子錶達而對血瘀證病理變化有一定影響。雌激素可能通過改善血瘀而影響骨質疏鬆的髮生。
혈어여골질소송관계밀절。혈어증병리변화적현대물질기출연구시당금연구적일개열점。연구표명혈관내피상관인자여혈어적형성관계밀절，자격소통과촉진NO、PGI2등혈관서장활성인자적표체，억제ET、Ang Ⅱ、TXA2등혈관수축인자표체이대혈어증병리변화유일정영향。자격소가능통과개선혈어이영향골질소송적발생。
Blood stasis is closely related to osteoporosis.The modern material and basic research of the pathological changes of blood stasis syndrome is a hot topic today.Studies have shown that the formation of blood stasis is closely related to the vascular endothelial-associated factors.Estrogen can affect the pathological changes of blood stasis syndrome by promoting the expression of vasodilation activity factors such as NO and PGI2, and inhibiting the expression of vascular contraction factors such as ET, Ang II, and TXA2.Estrogen may affected the occurrence of osteoporosis by improving blood stasis.
