CAJ | 학술논문

随着载人空间站发展，在军事和民用都有着巨大应用价值，载人航天器围绕地球旋转时，由于离心力与重力相平衡，理论上其内部为零重力，这称之为失重。对于失重下的减少骨量丢失，药物预防或者治疗尚未达到理想的效果，并不能阻止失重状态下骨量的丢失，目前的研究证明了采用机械振动的方法可能是一种有效防治失重性骨质疏松的措施。因此本文对机械振动在动物、细胞、临床方面的研究现状以及防治失重性骨质疏松方面的临床应用前景进行综述。
수착재인공간참발전，재군사화민용도유착거대응용개치，재인항천기위요지구선전시，유우리심력여중력상평형，이론상기내부위령중력，저칭지위실중。대우실중하적감소골량주실，약물예방혹자치료상미체도이상적효과，병불능조지실중상태하골량적주실，목전적연구증명료채용궤계진동적방법가능시일충유효방치실중성골질소송적조시。인차본문대궤계진동재동물、세포、림상방면적연구현상이급방치실중성골질소송방면적림상응용전경진행종술。
With the development of manned space station, it has a huge value in both military and civilian application.When the manned spacecraft rotates around the earth, because of the equilibrium between the centrifugal force and the gravity, in theory, its internal gravity is zero, which is called weightlessness.For the bone loss under weightlessness, the drug prevention or treatment has not yet reached the ideal result, and it bone mass loss cannot be prevented under the state of weightlessness.The recent research proves that mechanical vibration may be an effective method for the prevention and treatment of bone mass loss under the state of weightlessness.This article reviews the current research of the mechanical vibration on animals, cells, and clinical aspects and the prospect of its clinical application on the prevention and treatment of osteoporosis under the state of weightlessness.