CAJ | 학술논문

目的：探讨血管瘤型脑膜瘤的常规 MRI、DWI 特征及其病理学基础。方法回顾性分析7例经手术病理证实的血管瘤型脑膜瘤的常规 MRI、DWI 表现及其病理特征,测量肿瘤及对侧正常脑实质 ADC 值,并进行对比分析。结果7例血管瘤型脑膜瘤中5例位于大脑凸面(额部4例,顶部1例),2例位于鞍旁。常规 MRI 序列6例肿瘤呈长 T1长 T2信号,1例呈等 T1等 T2信号。5例肿瘤 FLAIR 序列可见明显瘤周水肿,2例可见肿瘤内部坏死,6例肿瘤内部可见流空血管影,所有肿瘤 T1 WI 增强序列均呈明显强化。7例肿瘤平均 ADC 值(1.35×10-3 mm2/s)大于对侧正常脑实质(0.92×10-3 mm2/s)(t=7.21,P <0.01)。病理切片7例肿瘤内均可见成熟血管成分,免疫组化肿瘤细胞6例波形蛋白染色(Vim)阳性,1例散在阳性,7例上皮膜抗原(EMA)均阳性。结论血管瘤型脑膜瘤 MRI 表现具有一定特征性,与肿瘤富有血管成分有关。病灶 ADC 值较健侧增高,有助于此肿瘤的诊断。
목적：탐토혈관류형뇌막류적상규 MRI、DWI 특정급기병이학기출。방법회고성분석7례경수술병리증실적혈관류형뇌막류적상규 MRI、DWI 표현급기병리특정,측량종류급대측정상뇌실질 ADC 치,병진행대비분석。결과7례혈관류형뇌막류중5례위우대뇌철면(액부4례,정부1례),2례위우안방。상규 MRI 서렬6례종류정장 T1장 T2신호,1례정등 T1등 T2신호。5례종류 FLAIR 서렬가견명현류주수종,2례가견종류내부배사,6례종류내부가견류공혈관영,소유종류 T1 WI 증강서렬균정명현강화。7례종류평균 ADC 치(1.35×10-3 mm2/s)대우대측정상뇌실질(0.92×10-3 mm2/s)(t=7.21,P <0.01)。병리절편7례종류내균가견성숙혈관성분,면역조화종류세포6례파형단백염색(Vim)양성,1례산재양성,7례상피막항원(EMA)균양성。결론혈관류형뇌막류 MRI 표현구유일정특정성,여종류부유혈관성분유관。병조 ADC 치교건측증고,유조우차종류적진단。
Objective To explore the conventional MRI,diffusion-weighted imaging (DWI)characteristics and the pathological basis of angiomatous meningioma.Methods The conventional MRI,DWI and pathological manifestations of 7 cases with angioma-tous meningioma confirmed by surgery and pathology were analyzed retrospectively.The apparent diffusion coefficient (ADC)value of the tumors and contralateral normal brain parenchyma were measured and compared with each other.Results Among the 7 ca-ses,5 cases were in the convexity of brain (4 cases in the frontal part and 1 case in the parietal part),and 2 cases in the parasella. 6 cases showed hypointense on T1 WI and hyperintense on T2 WI,and 1 case showed isointense on both T1 WI and T2 WI.The necro-sis within the tumor was seen in 2 cases.The flowing void phenomenon was seen in 6 cases.The significant peritumoral edema was seen in 5 cases on FLAIR.Significant enhancement on contrast-enhanced T1 WI was seen in all the cases.The average ADC value of the tumors (1.35×10 -3 mm2/s)was significently higher than that of the contralateral normal parenchyma (0.92 × 10 -3 mm2/s) (t=7.21,P <0.01).Mature vessel component was seen on pathological section in all the cases.For immunohistochemically analy-sis,the expression of vimentin (Vim)was positive in 6 cases and scattered positive in 1 case.The expression of epithelial membrane antigen (EMA)was positive in all the cases.Conclusion The MRI features of angiomatous meningioma are closely correlated with rich blood vessels.The ADC value of the tumor is higher than that of the contralateral parenchyma,which is helpful for the diagno-sis.