世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2014年
6期
796-799
,共4页
内蒙古野生甘草%质量评价指标%药效组分%四君子汤
內矇古野生甘草%質量評價指標%藥效組分%四君子湯
내몽고야생감초%질량평개지표%약효조분%사군자탕
Liquorice%Quality standard indicators%Active components alignments%Sijunzi decoction
目的:以内蒙古野生炙甘草单味药、药对、复方为研究载体,测定甘草中4种药效组分含量,探索药效组分变化规律。方法:采用单味药、药对配伍、复方配伍组分-液相色谱综合分析法。结果:药效组分甘草苷-甘草素-甘草酸-异甘草苷在单味药(内蒙古野生炙甘草)中含量为(12.14±0.31),(3.25±0.19),(38.75±1.77),(1.4±0.25);在药对(炙甘草-人参)中含量为(2.87±0.04),(0.74±0.02),(6.42±0.18),(0.37±0.03);在药对(炙甘草-白术)中含量为(5.99±0.01),(2.16±0.09),(22.4±1.8),(0.77±0.02):在复方(四君子汤)中含量为(2.99±0.03),(0.81±0.04),(10.05±0.31),(0.32±0.03)。结论:甘草中4中药效组分在单味药、药对、复方中含量存在一定差异,为进一步完善甘草药材质量的制定提供新思路和科学依据。
目的:以內矇古野生炙甘草單味藥、藥對、複方為研究載體,測定甘草中4種藥效組分含量,探索藥效組分變化規律。方法:採用單味藥、藥對配伍、複方配伍組分-液相色譜綜閤分析法。結果:藥效組分甘草苷-甘草素-甘草痠-異甘草苷在單味藥(內矇古野生炙甘草)中含量為(12.14±0.31),(3.25±0.19),(38.75±1.77),(1.4±0.25);在藥對(炙甘草-人參)中含量為(2.87±0.04),(0.74±0.02),(6.42±0.18),(0.37±0.03);在藥對(炙甘草-白術)中含量為(5.99±0.01),(2.16±0.09),(22.4±1.8),(0.77±0.02):在複方(四君子湯)中含量為(2.99±0.03),(0.81±0.04),(10.05±0.31),(0.32±0.03)。結論:甘草中4中藥效組分在單味藥、藥對、複方中含量存在一定差異,為進一步完善甘草藥材質量的製定提供新思路和科學依據。
목적:이내몽고야생자감초단미약、약대、복방위연구재체,측정감초중4충약효조분함량,탐색약효조분변화규률。방법:채용단미약、약대배오、복방배오조분-액상색보종합분석법。결과:약효조분감초감-감초소-감초산-이감초감재단미약(내몽고야생자감초)중함량위(12.14±0.31),(3.25±0.19),(38.75±1.77),(1.4±0.25);재약대(자감초-인삼)중함량위(2.87±0.04),(0.74±0.02),(6.42±0.18),(0.37±0.03);재약대(자감초-백술)중함량위(5.99±0.01),(2.16±0.09),(22.4±1.8),(0.77±0.02):재복방(사군자탕)중함량위(2.99±0.03),(0.81±0.04),(10.05±0.31),(0.32±0.03)。결론:감초중4중약효조분재단미약、약대、복방중함량존재일정차이,위진일보완선감초약재질량적제정제공신사로화과학의거。
Objective:To explore regularity of the active components alignments (ACA)through determination of the ACA in inner Mon-golia wild licorice single herb,herb-herb and prescription.Methods:The ACA were determined by reversed phase high-performance liq-uid chromatography (RP-HPLC)in single herb,herb-herb and prescription.Results:The contents of liquiritin-liquiritigenin-glycyrrhizin acid-Isoliquiritin in single liquorice herb were(12.14 ±0.31),(3.25 ±0.19),(38.75 ±1.77),(l1.4 ±0.25;in herb-herb (honey-fried licorice-ginseng)were(2.87 ±0.04),(0.74 ±0.02),(6.42 ±0.18),(0.37 ±0.03);in herb-herb(honey-fried licorice - big-head atractylodes rhizome )were (5.99 ±0.01),(2.16 ±0.09),(22.4 ±1.8),(0.77 ±0.02);in prescription were(2.99 ±0.03), (0.81 ±0.04),(10.05 ±0.31),(0.32 ±0.03).Conclusion:There are some differences in the content of liquiritin- liquiritigenin-glycyrrhizic acid-Isoliquiritinin in single herb,herb-herb and prescription,which provides scientific basis and a new way for the establish-ment of improving the quality of licorice.