海峡药学
海峽藥學
해협약학
STRAIT PHARMACEUTICAL JOURNAL
2014年
6期
42-44
,共3页
胡水保%李海龙%陈琳婉%王国付
鬍水保%李海龍%陳琳婉%王國付
호수보%리해룡%진림완%왕국부
玛咖%松花粉%抗疲劳
瑪咖%鬆花粉%抗疲勞
마가%송화분%항피로
Maca%Pine pollen%Antifatigue
目的:研究玛咖松花粉合剂对小鼠抗运动性疲劳的作用。方法采用四批雄性 Balb/c小鼠,每批50只,按照体重分为5个实验组,分别给予生理盐水(15mL/(kg· d))、玛咖松花粉合剂0.5g/(kg· d)、1.0g/(kg· d)、2.5g/(kg· d),红牛饮料(15mL/(kg· d)),连续灌胃30d后分别测定各组小鼠游泳时间、尿素氮、肝糖原、血乳酸、谷草转氨酶和谷丙转氨酶含量。结果玛咖松花粉合剂能显著延长小鼠游泳时间(P <0.05),降低运动后小鼠血尿素氮含量,增加肝糖原含量(P<0.05),快速降低血乳酸(P<0.05),且谷草转氨酶和谷丙转氨酶含量与阴性对照组无明显差异( P>0.05)。结论玛咖松花粉合剂具有抗小鼠运动性疲劳的作用。它是通过提高运动耐力,增加肝糖原储备,加速乳酸的清除来抗运动性疲劳的,同时玛咖松花粉合剂对小鼠肝功能均无影响。
目的:研究瑪咖鬆花粉閤劑對小鼠抗運動性疲勞的作用。方法採用四批雄性 Balb/c小鼠,每批50隻,按照體重分為5箇實驗組,分彆給予生理鹽水(15mL/(kg· d))、瑪咖鬆花粉閤劑0.5g/(kg· d)、1.0g/(kg· d)、2.5g/(kg· d),紅牛飲料(15mL/(kg· d)),連續灌胃30d後分彆測定各組小鼠遊泳時間、尿素氮、肝糖原、血乳痠、穀草轉氨酶和穀丙轉氨酶含量。結果瑪咖鬆花粉閤劑能顯著延長小鼠遊泳時間(P <0.05),降低運動後小鼠血尿素氮含量,增加肝糖原含量(P<0.05),快速降低血乳痠(P<0.05),且穀草轉氨酶和穀丙轉氨酶含量與陰性對照組無明顯差異( P>0.05)。結論瑪咖鬆花粉閤劑具有抗小鼠運動性疲勞的作用。它是通過提高運動耐力,增加肝糖原儲備,加速乳痠的清除來抗運動性疲勞的,同時瑪咖鬆花粉閤劑對小鼠肝功能均無影響。
목적:연구마가송화분합제대소서항운동성피로적작용。방법채용사비웅성 Balb/c소서,매비50지,안조체중분위5개실험조,분별급여생리염수(15mL/(kg· d))、마가송화분합제0.5g/(kg· d)、1.0g/(kg· d)、2.5g/(kg· d),홍우음료(15mL/(kg· d)),련속관위30d후분별측정각조소서유영시간、뇨소담、간당원、혈유산、곡초전안매화곡병전안매함량。결과마가송화분합제능현저연장소서유영시간(P <0.05),강저운동후소서혈뇨소담함량,증가간당원함량(P<0.05),쾌속강저혈유산(P<0.05),차곡초전안매화곡병전안매함량여음성대조조무명현차이( P>0.05)。결론마가송화분합제구유항소서운동성피로적작용。타시통과제고운동내력,증가간당원저비,가속유산적청제래항운동성피로적,동시마가송화분합제대소서간공능균무영향。
OBJECTIVE To study the antifatigue function of Maca and Pine pollen mixture to mouse.METHODS 4 experiments were carried out , in each of which 50 Balb/c male mice were used and they were divided into 5 groups:saline (15mL/(kg· d)),Maca and Pine pollen mixture 0.5g/(kg· d),1.0g/(kg· d),2.5g/(kg· d),Red Bull (15mL/(kg· d)) were given respectively by american ginseng ,content of ured nitro-gen、hepatic glycogen、blood lactic、AST and ALT were determined for 30days.The fourtestswere used to determine swimming time.RESULTS Maca and Pine pollen mixture could extend swimming time withweight loading in mice (P<0.05),reduce urea nitrogen after exercise (P<0.05),increase hepatic glycogen (P<0.05) and decrease the blood lactose ( P<0.05 ) ,and had no effects on AST and ALT ( P>0.05 ).CONCLUSION Maca and Pine pollen mixture can relieve physical fatigue.It can improve exercise tolerance ,increase hepatic glycogen ,speed up the remov-al of blood lactose to antifatigue ,and had no effect on liver function.