CAJ | 학술논문

目的：探讨氯胺酮、异丙酚复合利多卡因用于小儿手术麻醉的效果。方法我院于2008年1月至2013年1月收治行会阴部或腹部手术的患儿98例，随机分为观察组（46例）与对照组（52例）。观察组采用氯胺酮、异丙酚复合利多卡因麻醉，对照组采用氯胺酮麻醉，比较和分析两组患儿生命体征与不良反应的发生。结果观察组与对照组患儿在麻醉前5 min、麻醉后5 min、15 min和30 min的呼吸（RR）、脉搏（HR）、收缩压（SBP）、血氧饱和度（SpO2）水平差异无统计学意义（P＞0．05）。对照组出现麻醉不良反应32例，其中恶心或呕吐11例、舌后坠4例、需要吸痰8例、出现精神反应9例；观察组出现麻醉不良反应6例，其中恶心或呕吐4例，出现精神反应2例。观察组不良反应发生率显著低于对照组，差异有统计学意义（P＜0．05）。结论氯胺酮、异丙酚复合利多卡因应用于小儿手术麻醉，麻醉效果理想，不良反应发生率低，值得临床推广。
목적：탐토록알동、이병분복합리다잡인용우소인수술마취적효과。방법아원우2008년1월지2013년1월수치행회음부혹복부수술적환인98례，수궤분위관찰조（46례）여대조조（52례）。관찰조채용록알동、이병분복합리다잡인마취，대조조채용록알동마취，비교화분석량조환인생명체정여불량반응적발생。결과관찰조여대조조환인재마취전5 min、마취후5 min、15 min화30 min적호흡（RR）、맥박（HR）、수축압（SBP）、혈양포화도（SpO2）수평차이무통계학의의（P＞0．05）。대조조출현마취불량반응32례，기중악심혹구토11례、설후추4례、수요흡담8례、출현정신반응9례；관찰조출현마취불량반응6례，기중악심혹구토4례，출현정신반응2례。관찰조불량반응발생솔현저저우대조조，차이유통계학의의（P＜0．05）。결론록알동、이병분복합리다잡인응용우소인수술마취，마취효과이상，불량반응발생솔저，치득림상추엄。
Objective To evaluate the anesthetic effect of ketamine combined with propofol and lidocaine in the pediatric surgery. Methods A total of 98 pediatric patients admitted to our hospital during January 2008 to January 201 3 for perineal or abdominal surgical treatment were randomly divided into two groups,observation group (46 cases)and control group (52 cases).Pediatric patients of observation group were anesthetized by combined with propofol and lidocaine,and in control group only ketamine was used in operation.The vital signs and occurrence of adverse reactions during surgical procedures were observed.Results The vital signs of patients in two groups,which in-cluded respiratory rate (RR),heart rate (HR),systolic blood pressure(SBP),pulse oxygen saturation (SpO2 ),were recorded at time points of 5 minutes before induction of anesthesia,5 min after anesthesia,1 5 min and 30 min during operation.There were no significant differences between observation group and control group in RR,HR,SBP,and SpO2 at different time points (P>0.05 ).The incidence of adverse reac-tions in observation group was significantly lower than that in control group (P<0.05).Thirty-two cases of anesthesia adverse reactions ap-peared in control group,including nausea or vomiting in 1 1 cases,suctioning in 8 cases,mental reaction in 9 cases and glossocoma in 4 cases. However,there were only 6 cases undergoing anesthesia adverse reactions in observation group,including nausea or vomiting in 4 cases,and mental reaction in 2 cases.Conclusion Ketamine combined with propofol and lidocaine in the anesthesia of the pediatric surgery is relatively stable and effective,and has lower anesthesia adverse reactions.Therefore,the anesthesia by using ketamine combined with propofol and lido-caine is more suitable for pediatric operation.