中华医学超声杂志(电子版)
中華醫學超聲雜誌(電子版)
중화의학초성잡지(전자판)
CHINESE JOURNAL OF MEDICAL ULTRASOUND(ELECTRONICAL VISION)
2014年
7期
593-597
,共5页
超声检查%甲状腺结节%钙化
超聲檢查%甲狀腺結節%鈣化
초성검사%갑상선결절%개화
Ultrasonography%Thyroid nodule%Calciifcation
目的:探讨不同类型钙化对甲状腺良恶性结节的鉴别诊断价值。方法2013年1至10月在华中科技大学同济医学院附属同济医院行甲状腺超声检查的195例患者共258个结节。重点观察甲状腺结节数目、回声以及结节内钙化灶的大小、形态和分布,将不同钙化模式分为3型:Ⅰ型微小点状微钙化,Ⅱ型粗大钙化,Ⅲ型周边钙化。结果甲状腺恶性结节钙化率为68.6%(81/118),高于甲状腺良性结节钙化率40.0%(56/140),且差异有统计学意义(χ2=21.096,P<0.01)。Ⅰ型微小点状微钙化在甲状腺恶性结节中的发生率为72.8%(59/81),高于其在甲状腺良性结节中的发生率41.1%(23/56),且差异有统计学意义(χ2=13.906,P<0.01)。Ⅱ型粗钙化在甲状腺良恶性结节中的发生率差异无统计学意义[23.5%(19/81)vs 37.5%(21/56),χ2=3.159,P>0.05]。Ⅲ型周边钙化在甲状腺良性结节中的发生率为21.4%(12/56),高于其在甲状腺恶性结节中的发生率3.7%(3/81),且差异有统计学意义(χ2=10.669,P<0.05)。伴钙化的甲状腺单发结节、甲状腺极低回声结节恶变率分别为85.3%(58/68)、76.2%(48/63),均高于伴钙化的甲状腺多发结节、甲状腺其他回声结节恶变率33.3%(23/69)、44.6%(33/74),且差异均有统计学意义(χ2=38.261、14.057,均P<0.01)。结论甲状腺结节内每种钙化都存在恶性风险,不同类型钙化对于甲状腺良恶性结节的鉴别具有重要价值。
目的:探討不同類型鈣化對甲狀腺良噁性結節的鑒彆診斷價值。方法2013年1至10月在華中科技大學同濟醫學院附屬同濟醫院行甲狀腺超聲檢查的195例患者共258箇結節。重點觀察甲狀腺結節數目、迴聲以及結節內鈣化竈的大小、形態和分佈,將不同鈣化模式分為3型:Ⅰ型微小點狀微鈣化,Ⅱ型粗大鈣化,Ⅲ型週邊鈣化。結果甲狀腺噁性結節鈣化率為68.6%(81/118),高于甲狀腺良性結節鈣化率40.0%(56/140),且差異有統計學意義(χ2=21.096,P<0.01)。Ⅰ型微小點狀微鈣化在甲狀腺噁性結節中的髮生率為72.8%(59/81),高于其在甲狀腺良性結節中的髮生率41.1%(23/56),且差異有統計學意義(χ2=13.906,P<0.01)。Ⅱ型粗鈣化在甲狀腺良噁性結節中的髮生率差異無統計學意義[23.5%(19/81)vs 37.5%(21/56),χ2=3.159,P>0.05]。Ⅲ型週邊鈣化在甲狀腺良性結節中的髮生率為21.4%(12/56),高于其在甲狀腺噁性結節中的髮生率3.7%(3/81),且差異有統計學意義(χ2=10.669,P<0.05)。伴鈣化的甲狀腺單髮結節、甲狀腺極低迴聲結節噁變率分彆為85.3%(58/68)、76.2%(48/63),均高于伴鈣化的甲狀腺多髮結節、甲狀腺其他迴聲結節噁變率33.3%(23/69)、44.6%(33/74),且差異均有統計學意義(χ2=38.261、14.057,均P<0.01)。結論甲狀腺結節內每種鈣化都存在噁性風險,不同類型鈣化對于甲狀腺良噁性結節的鑒彆具有重要價值。
목적:탐토불동류형개화대갑상선량악성결절적감별진단개치。방법2013년1지10월재화중과기대학동제의학원부속동제의원행갑상선초성검사적195례환자공258개결절。중점관찰갑상선결절수목、회성이급결절내개화조적대소、형태화분포,장불동개화모식분위3형:Ⅰ형미소점상미개화,Ⅱ형조대개화,Ⅲ형주변개화。결과갑상선악성결절개화솔위68.6%(81/118),고우갑상선량성결절개화솔40.0%(56/140),차차이유통계학의의(χ2=21.096,P<0.01)。Ⅰ형미소점상미개화재갑상선악성결절중적발생솔위72.8%(59/81),고우기재갑상선량성결절중적발생솔41.1%(23/56),차차이유통계학의의(χ2=13.906,P<0.01)。Ⅱ형조개화재갑상선량악성결절중적발생솔차이무통계학의의[23.5%(19/81)vs 37.5%(21/56),χ2=3.159,P>0.05]。Ⅲ형주변개화재갑상선량성결절중적발생솔위21.4%(12/56),고우기재갑상선악성결절중적발생솔3.7%(3/81),차차이유통계학의의(χ2=10.669,P<0.05)。반개화적갑상선단발결절、갑상선겁저회성결절악변솔분별위85.3%(58/68)、76.2%(48/63),균고우반개화적갑상선다발결절、갑상선기타회성결절악변솔33.3%(23/69)、44.6%(33/74),차차이균유통계학의의(χ2=38.261、14.057,균P<0.01)。결론갑상선결절내매충개화도존재악성풍험,불동류형개화대우갑상선량악성결절적감별구유중요개치。
Objective To investigate the differential diagnostic signiifcance of different calciifcation types in thyroid benign and malignant nodules with high-frequency ultrasound. Methods Totally 195 patients with thyroid lesions were examined on conventional high-frequency ultrasound pre-operatively. The evaluation was foucsed on the number and echo of thyroid nodules and the size, shape and distribution of calciifcation inside. Different calciifcation patterns were divided into 3 types:type 1 micro-calciifcation, type 2 coarse calciifcation, type 3 peripheral calciifcation. Results The calciifcation rate of thyroid malignant nodules 68.6%(81/118) was signiifcantly higher than that of benign nodules 40.0%(56/140) (χ2=21.096, P<0.01). The ratio of type 1 calciifcation in malignant nodules 72.8%(59/81) was obviously higher than that of benign nodules 41.1%(23/56) (χ2=13.906, P<0.01). There was no signiifcant difference of type 2 calciifcation between malignant and benign nodules (χ2=3.159, P>0.05). The incidence of type 3 calcification in malignant lesions 3.7%(3/81) was lower than that of benign nodules 21.4%(12/56) (χ2=10.669, P<0.05). The malignancy incidence of solitary thyroid nodule 85.3%(58/68) and extremely low echo nodules with calciifcation 76.2%(48/63) was higher than that of multiple thyroid nodules 33.3%(23/69) and other echo nodules 44.6%(33/74) (χ2=38.261, 14.057, both P<0.01). Conclusions There was potential risk of malignancy in each calciifcation of thyroid nodules. Different calciifcation types had important value for differential diagnosis of benign and malignant thyroid nodules.