国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
7期
1275-1277
,共3页
蔡玉莲%谢杨春%苏蓉%钱道卫%伍岚%岳建军
蔡玉蓮%謝楊春%囌蓉%錢道衛%伍嵐%嶽建軍
채옥련%사양춘%소용%전도위%오람%악건군
灯盏花素%碱烧伤%角膜
燈盞花素%堿燒傷%角膜
등잔화소%감소상%각막
Breviscapine%alkali burn%cornea
目的:期望能找到更好治疗眼碱烧伤,减少病患痛苦,减轻社会负担的方法。<br> 方法:选择眼碱烧伤患者100例。根据化学烧伤程度分级分为4大组,每大组再随机分为对照组和治疗组各约一半。对照组行常规治疗,治疗组在观察组的基础上加用灯盏花素注射液40 mg静滴。观察两组角膜恢复时间、视力变化、角膜混浊程度、角膜新生血管数量、其它并发症等。统计分析其疗效。<br> 结果:治疗四大组患者中Ⅰ级的治疗组与对照组各项指标对比无显著性差异(P>0.05),Ⅱ,Ⅲ,Ⅳ级的各项指标对比均有显著性差异(P<0.05)。其角膜混浊程度与新生血管数量对比,治疗组明显优于对照组(P<0.05)。<br> 结论:灯盏花素治疗眼碱烧伤能缩短疗程,减少角膜瘢痕,提高视力。
目的:期望能找到更好治療眼堿燒傷,減少病患痛苦,減輕社會負擔的方法。<br> 方法:選擇眼堿燒傷患者100例。根據化學燒傷程度分級分為4大組,每大組再隨機分為對照組和治療組各約一半。對照組行常規治療,治療組在觀察組的基礎上加用燈盞花素註射液40 mg靜滴。觀察兩組角膜恢複時間、視力變化、角膜混濁程度、角膜新生血管數量、其它併髮癥等。統計分析其療效。<br> 結果:治療四大組患者中Ⅰ級的治療組與對照組各項指標對比無顯著性差異(P>0.05),Ⅱ,Ⅲ,Ⅳ級的各項指標對比均有顯著性差異(P<0.05)。其角膜混濁程度與新生血管數量對比,治療組明顯優于對照組(P<0.05)。<br> 結論:燈盞花素治療眼堿燒傷能縮短療程,減少角膜瘢痕,提高視力。
목적:기망능조도경호치료안감소상,감소병환통고,감경사회부담적방법。<br> 방법:선택안감소상환자100례。근거화학소상정도분급분위4대조,매대조재수궤분위대조조화치료조각약일반。대조조행상규치료,치료조재관찰조적기출상가용등잔화소주사액40 mg정적。관찰량조각막회복시간、시력변화、각막혼탁정도、각막신생혈관수량、기타병발증등。통계분석기료효。<br> 결과:치료사대조환자중Ⅰ급적치료조여대조조각항지표대비무현저성차이(P>0.05),Ⅱ,Ⅲ,Ⅳ급적각항지표대비균유현저성차이(P<0.05)。기각막혼탁정도여신생혈관수량대비,치료조명현우우대조조(P<0.05)。<br> 결론:등잔화소치료안감소상능축단료정,감소각막반흔,제고시력。
AlM:To find better ways of treating ocular alkali burn, and to reduce the suffering of patients and social burden.METHODS:Totally 100 patients were graded according to the degree of chemical burns to four major groups, each half were randomly divided into the control group and the treatment group. Control group underwent conventional treatment. ln addition to conventional therapy, patients in each treatment group were also added a Breviscapine intravenous injection of 40mg daily. Corneal recovery time, changes in vision, degree of corneal opacity, number of corneal neovascularization and other complications were observed. Curative effects were analyzed statistically. <br> RESULTS:There was no significant difference in levelⅠgroup between control group and treatment group ( P>0. 05); There were significantly different in level Ⅱ, Ⅲand Ⅳ group ( P<0. 05 ). Compared to the degree of corneal opacity and the number of corneal neovascularization, the treatment group was obviously better than the control group(P<0. 05). <br> CONCLUSlON: Breviscapine in the treatment of ocular alkali burns can shorten the course of treatment, reduce corneal scarring, and improve vision.