CAJ | 학술논문

目的：探讨小儿细菌性肺炎的病原菌及其耐药性。方法2382例确诊为细菌性肺炎患儿痰培养标本为研究对象，分析其感染病原菌的分布及耐药性情况。结果小儿细菌性肺炎病原菌以革兰阴性菌为主，共477株，占比83.45%，其中肺炎克雷伯菌26.44%，大肠埃希菌25.22%，鲍氏不动杆菌10.68%；革兰阳性菌共64株，占比11.23%，其中金黄色葡萄球菌7.71%。阿米卡星、亚胺培南对各种病原菌均较敏感，美洛培南除对鲍氏不动杆菌不敏感外，对其他菌类均敏感；环丙沙星、庆大霉素对金黄色葡萄球菌均较为敏感，氨苄西林对肺炎克雷伯菌、大肠埃希菌、鲍氏不动杆菌、阴沟肠杆菌、铜绿假单胞菌的敏感性均较差。结论小儿细菌性肺炎病原菌以革兰阴性菌为主，临床用药应以药敏试验为指导，合理使用抗生素，避免或减少细菌耐药性的产生。
목적：탐토소인세균성폐염적병원균급기내약성。방법2382례학진위세균성폐염환인담배양표본위연구대상，분석기감염병원균적분포급내약성정황。결과소인세균성폐염병원균이혁란음성균위주，공477주，점비83.45%，기중폐염극뢰백균26.44%，대장애희균25.22%，포씨불동간균10.68%；혁란양성균공64주，점비11.23%，기중금황색포도구균7.71%。아미잡성、아알배남대각충병원균균교민감，미락배남제대포씨불동간균불민감외，대기타균류균민감；배병사성、경대매소대금황색포도구균균교위민감，안변서림대폐염극뢰백균、대장애희균、포씨불동간균、음구장간균、동록가단포균적민감성균교차。결론소인세균성폐염병원균이혁란음성균위주，림상용약응이약민시험위지도，합리사용항생소，피면혹감소세균내약성적산생。
Objective To investigate pathogens and drug resistance pediatric bacterial pneumonia. Methods From January 1, 2010 to December 31, 2012, 2382 cases of bacterial pneumonia in pediatric patients sputum culture samples as objects, analyzed the distribution of pathogens and drug resistance. Results Pediatric bacterial pneumonia pathogens mainly gram-negative bacteria, a total of 477, accounting for 83.45%, Klebsiella pneumoniae account for 26.44%, Escherichia coli for 25.22%, Acinetobacter spp 10.68%;gram-negative bacteria were 64, accounting for 11.23%, of which 7.71%of staphylococcus aureus. Amikacin and imipenem were sensitive to various pathogens, meropenem was sensitive to other fungus except for acinetobacter baumannii;ciprofloxacin, gentamicin were more sensitive to staphylococcus aureus, ampicillin were poor sensitive to Klebsiella pneumoniae, Escherichia coli, acinetobacter baumannii, enterobacter cloacae, pseudomonas aeruginosa . Conclusion Pediatric bacterial pneumonia pathogens mainly gram-negative bacteria, clinical treatment should be based on susceptibility testing and rational use of antibiotics to prevent or reduce bacterial drug resistance.