CAJ | 학술논문

目的：研究翻白草及复方翻白草汤剂的降血糖作用。方法：将翻白草汤剂及复方翻白草汤剂浓缩后，分别以4.1 ml·kg-1（1ml含生药1g）和5.8ml·kg-1（1ml含生药2g）对两组家兔灌胃给药7d，同时与美吡哒和生理盐水进行对照，用葡萄糖氧化酶法测定血糖，观察正常家兔的血糖变化。结果：翻白草汤剂及复方翻白草汤剂，对正常家兔血糖有明显影响。正常对照组为（0.50±0.32）mmol· L-1，翻白草汤剂组为（3.58±1.48）mmol·L-1（P＜0.01），复方翻白草汤剂组为（4.29±2.21）mmol·L-1（P＜0.01）。结论：翻白草汤剂及复方翻白草汤剂对正常家兔均有降血糖作用。
목적：연구번백초급복방번백초탕제적강혈당작용。방법：장번백초탕제급복방번백초탕제농축후，분별이4.1 ml·kg-1（1ml함생약1g）화5.8ml·kg-1（1ml함생약2g）대량조가토관위급약7d，동시여미필달화생리염수진행대조，용포도당양화매법측정혈당，관찰정상가토적혈당변화。결과：번백초탕제급복방번백초탕제，대정상가토혈당유명현영향。정상대조조위（0.50±0.32）mmol· L-1，번백초탕제조위（3.58±1.48）mmol·L-1（P＜0.01），복방번백초탕제조위（4.29±2.21）mmol·L-1（P＜0.01）。결론：번백초탕제급복방번백초탕제대정상가토균유강혈당작용。
Objective:to study the hypoglycemic effect of Potentilla Discolor Bunge and the medicinal broth of compound Po-tentilla Discolor Bungeon Method:having concentrated the medicinal broth of compound Potentilla Discolor Bungeon and compound the medicinal broth of compound Potentilla Discolor Bungeon,adopting 7 d gavage administration for two groups of rabbits with 4.1ml.Kg-1 (1ml containing crude drug with 1g)and 5.8 ml.Kg-1 (1ml containing crude drug with 2g),simultaneously compa-ring with minidiab and normal saline then determining blood sugar by glucose oxidase ultimately observing blood sugar change about normal rabbits.Results:the medicinal broth of compound Potentilla Discolor Bungeon and the compound medicinal broth of com-pound Potentilla Discolor Bungeon had significant effect on the blood sugar on normal rabbits.normal control group (0.50 ±0.32) mmol.L-1,the medicinal broth of compound Potentilla Discolor Bungeon (3.58 ±1.48)mmol.L-1 (P<0.01),the com-pound medicinal broth of compound Potentilla Discolor Bungeon (4.29 ±2.21 ) mmol.L-1 (P<0.01 ).Conclusion:the me-dicinal broth of Potentilla Discolor Bungeon and compound medicinal broth of Potentilla Discolor Bungeon have hypoglycemic action for normal rabbits.