医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2014年
12期
1545-1546,1568
,共3页
无创机械通气%慢性阻塞性肺疾病%呼吸衰竭
無創機械通氣%慢性阻塞性肺疾病%呼吸衰竭
무창궤계통기%만성조새성폐질병%호흡쇠갈
Noninvasive mechanical ventilation%Chronic obstructive pulmonary disease%Respiratory failure
目的：探讨无创机械通气对慢性阻塞性肺疾病并发呼吸衰竭患者治疗的有效性。方法：将80例慢性阻塞性肺疾病并发呼吸衰竭患者随机分为治疗组和对照组，各40例。治疗组采用传统抗感染、平喘、化痰等治疗基础上加用无创机械通气治疗，而对照组则采用传统治疗，比较两组患者治疗后的症状改善情况、气管插管率，第3、6、12、24小时的呼吸频率（RR）、心率（HR）、血气分析的pH、PaO2、PaCO2指标变化及住院时间，评价治疗效果。结果：治疗组总有效率95.0％明显优于对照组72．5％，治疗组气管插管率12.5％明显低于对照组的10.0％，两组数据比较，具有统计学意义（P＜0.05），治疗组治疗后第3、6小时的 HR、RR、pH、PaO2、PaCO2平均值较治疗前明显改善（P＜0．05），而对照组以上各指标改善不明显（ P＞0．05），第12、24小时的以上各项指标两组患者均明显改善，且治疗组改善状况更明显（ P＜0．05）。治疗组患者住院时间平均为（13．27±2．31）d明显短于对照组（21．14±4．26）d。故治疗组临床疗效明显优于对照组。结论：应用无创机械通气治疗慢性阻塞性肺疾病并发呼吸衰竭，可显著改善患者临床症状，减少气管插管率，较快纠正酸中毒、减少住院时间，疗效肯定。
目的：探討無創機械通氣對慢性阻塞性肺疾病併髮呼吸衰竭患者治療的有效性。方法：將80例慢性阻塞性肺疾病併髮呼吸衰竭患者隨機分為治療組和對照組，各40例。治療組採用傳統抗感染、平喘、化痰等治療基礎上加用無創機械通氣治療，而對照組則採用傳統治療，比較兩組患者治療後的癥狀改善情況、氣管插管率，第3、6、12、24小時的呼吸頻率（RR）、心率（HR）、血氣分析的pH、PaO2、PaCO2指標變化及住院時間，評價治療效果。結果：治療組總有效率95.0％明顯優于對照組72．5％，治療組氣管插管率12.5％明顯低于對照組的10.0％，兩組數據比較，具有統計學意義（P＜0.05），治療組治療後第3、6小時的 HR、RR、pH、PaO2、PaCO2平均值較治療前明顯改善（P＜0．05），而對照組以上各指標改善不明顯（ P＞0．05），第12、24小時的以上各項指標兩組患者均明顯改善，且治療組改善狀況更明顯（ P＜0．05）。治療組患者住院時間平均為（13．27±2．31）d明顯短于對照組（21．14±4．26）d。故治療組臨床療效明顯優于對照組。結論：應用無創機械通氣治療慢性阻塞性肺疾病併髮呼吸衰竭，可顯著改善患者臨床癥狀，減少氣管插管率，較快糾正痠中毒、減少住院時間，療效肯定。
목적：탐토무창궤계통기대만성조새성폐질병병발호흡쇠갈환자치료적유효성。방법：장80례만성조새성폐질병병발호흡쇠갈환자수궤분위치료조화대조조，각40례。치료조채용전통항감염、평천、화담등치료기출상가용무창궤계통기치료，이대조조칙채용전통치료，비교량조환자치료후적증상개선정황、기관삽관솔，제3、6、12、24소시적호흡빈솔（RR）、심솔（HR）、혈기분석적pH、PaO2、PaCO2지표변화급주원시간，평개치료효과。결과：치료조총유효솔95.0％명현우우대조조72．5％，치료조기관삽관솔12.5％명현저우대조조적10.0％，량조수거비교，구유통계학의의（P＜0.05），치료조치료후제3、6소시적 HR、RR、pH、PaO2、PaCO2평균치교치료전명현개선（P＜0．05），이대조조이상각지표개선불명현（ P＞0．05），제12、24소시적이상각항지표량조환자균명현개선，차치료조개선상황경명현（ P＜0．05）。치료조환자주원시간평균위（13．27±2．31）d명현단우대조조（21．14±4．26）d。고치료조림상료효명현우우대조조。결론：응용무창궤계통기치료만성조새성폐질병병발호흡쇠갈，가현저개선환자림상증상，감소기관삽관솔，교쾌규정산중독、감소주원시간，료효긍정。
Objective :Research on the efficacy of Noninvasive mechanical ventilation in the treatment of chronic ob-structive pulmonary disease patients with respiratory failure .Methods :Divide 80 cases of chronic obstructive pulmonary disease patients with respiratory failure randomly into treatment group and control group each with 40 cases .The pa-tients in treatment group were treated with Noninvasive mechanical ventilation based on using the traditional anti-infec-tion ,asthma ,phlegm and other treatment ,while others in control group were treated with traditional treatment .Com-pare these 2 groups’improvement of symptoms ,rate of endotracheal intubation respiratory rate (RR) ,the heart rate (HR) ,blood gas analysis of pH ,PaO2 ,PaCO2 indicators in 3rd ,6th ,12th and 24th hour and hospitalization after treat-ment .Evaluate the therapeutic effect .Results:The total effective rate of treatment group was 95% ,significantly better than the control group ,72 .5% .Treatment group intubation rate is 1% ,significantly lower than the control group , 10% .These two sets of data were statistically significant (P< 0 .05) .The treatment group’s HR ,RR ,pH ,PaO2 , PaCO2 average values in 3rd ,6th hour significantly improved after treatment(P<0 .05) ,while the control group’s show no obvious improvement(P> 0 .05) .These values in 12th ,24th hour both improved significantly ,and the treatment group was more obvious(P<0 .05) .The treatment group’s average length of stay was (13 .27 ± 2 .31)days ,significant-ly shorter than the control group (21 .14 ± 4 .26)days .Clinical efficacy of the treatment group was significantly better than the control group .Conclusion:Using Noninvasive mechanical ventilation in curing chronic obstructive pulmonary disease patients with respiratory failure can significantly improve the clinical symptoms and reduce the rate of endotra-cheal intubation ,correct acidosis quickly ,and reduce hospitalization time .The efficacy is worthy of recognition .
