CAJ | 학술논문

目的：探讨金双歧（双歧杆菌乳杆菌三联活菌片）与消旋卡多曲联用治疗小儿秋季腹泻临床效果。方法选取该院2011年10月至2012年10月收治的小儿秋季腹泻患儿200例，采用随机数字表法分为对照组和观察组各100例。对照组患儿给予金双歧口服治疗，观察组患儿在对照组治疗基础上加用消旋卡多曲口服治疗；观察比较两组患儿临床治疗总有效率、临床症状消失时间及改善情况。结果观察组患儿临床治疗总有效率[92.0%（92/100）]高于对照组[73.0%（73/100）]，差异有统计学意义（P<0.05）；观察组患儿发热、呕吐消失时间明显短于对照组，差异均有统计学意义（P<0.05）；观察组患儿治疗后大便次数和腹泻时间较治疗前显著改善，且显著优于对照组，差异均有统计学意义（P<0.05）。结论金双歧联合消旋卡多曲治疗小儿秋季腹泻可有效缓解临床症状，缩短病程，具有临床应用价值。
목적：탐토금쌍기（쌍기간균유간균삼련활균편）여소선잡다곡련용치료소인추계복사림상효과。방법선취해원2011년10월지2012년10월수치적소인추계복사환인200례，채용수궤수자표법분위대조조화관찰조각100례。대조조환인급여금쌍기구복치료，관찰조환인재대조조치료기출상가용소선잡다곡구복치료；관찰비교량조환인림상치료총유효솔、림상증상소실시간급개선정황。결과관찰조환인림상치료총유효솔[92.0%（92/100）]고우대조조[73.0%（73/100）]，차이유통계학의의（P<0.05）；관찰조환인발열、구토소실시간명현단우대조조，차이균유통계학의의（P<0.05）；관찰조환인치료후대편차수화복사시간교치료전현저개선，차현저우우대조조，차이균유통계학의의（P<0.05）。결론금쌍기연합소선잡다곡치료소인추계복사가유효완해림상증상，축단병정，구유림상응용개치。
Objective To investigate therapeutic effect of Jinshuangqi (live combined bifidobacterium and lactobacillus tablets) combined with racecadotril on children with diarrhea. Methods Selected 200 children with chronic diarrhea from Octo-ber 2011 to October 2012 in this hospital and randomly divided into two groups including the control group and the observation group,100 of each group. The children of the control group were treated with oral Jinshuangqi while those of the observation group added with oral racecadotril on the basis of the treatment schedule of the control group. The overall response rate of treatment in clinic,clinic disappearance time,as well as improvement situation were studied and compared. Results The overall response rate of improvement in clinic of the observation group were 92.0%(92/100),which was higher than that of the control group [73.0%(73/100)];The difference was statistically significant(P<0.05). The clinic symptoms disappearance duration of diarrhea, fever and vomiting of the observation group were significantly shorter than that of the control group ,There were statistically sig-nificant difference between them(P<0.05). The stool frequency and duration time of diarrhea of the two groups after treatment were obviously improved than those before treatment,which were significantly superior than those of the control group with statistically significant difference(P<0.05). Conclusion Jinshuangqi combined with racecadotril on children with diarrhea can efficiently im-prove clinical symptoms,shorten ill course,which has clinic application value.