CAJ | 학술논문

目的：探讨微量元素以及血铅水平与儿童发生贫血的相关性，为临床防治贫血提供可参考依据。方法连续收集85例诊断为贫血的患儿作为病例组，同时从门诊随机抽取90例健康体检儿童作为对照组，对受试者进行微量元素（铁、锌、钙、镁、铜）及血铅水平的检测，分析检测结果与贫血程度的相关性。结果与对照组相比，病例组患儿血中铁、锌、镁浓度明显比较低，而钙、铅浓度明显高于对照组，2组间比较差异有统计学意义（P＜0．05）。2组血中铜浓度差异无统计学意义（P＞0．05）。随着患儿血中铁浓、锌、镁浓度的降低，钙、铅浓度的上升，贫血严重程度明显增加（P＜0．05）；而血中铜浓度变化对贫血程度影响不明显（P＞0．05）。血铁浓度与 Hb、RBC及 MCH 呈正相关（P＜0．05）；血锌浓度与 Hb及 MCH 呈正相关（P＜0．05）；血铅浓度与Hb、MCV及 MCH 呈负相关（P＜0．05）。结论多种微量元素浓度的变化及血铅水平的升高影响儿童贫血的严重程度，因此有必要对相关微量元素及血铅进行检测。
목적：탐토미량원소이급혈연수평여인동발생빈혈적상관성，위림상방치빈혈제공가삼고의거。방법련속수집85례진단위빈혈적환인작위병례조，동시종문진수궤추취90례건강체검인동작위대조조，대수시자진행미량원소（철、자、개、미、동）급혈연수평적검측，분석검측결과여빈혈정도적상관성。결과여대조조상비，병례조환인혈중철、자、미농도명현비교저，이개、연농도명현고우대조조，2조간비교차이유통계학의의（P＜0．05）。2조혈중동농도차이무통계학의의（P＞0．05）。수착환인혈중철농、자、미농도적강저，개、연농도적상승，빈혈엄중정도명현증가（P＜0．05）；이혈중동농도변화대빈혈정도영향불명현（P＞0．05）。혈철농도여 Hb、RBC급 MCH 정정상관（P＜0．05）；혈자농도여 Hb급 MCH 정정상관（P＜0．05）；혈연농도여Hb、MCV급 MCH 정부상관（P＜0．05）。결론다충미량원소농도적변화급혈연수평적승고영향인동빈혈적엄중정도，인차유필요대상관미량원소급혈연진행검측。
Objective To analyze the relationship between anemia and blood levels of lead and trace elements in children,and to provide basis for the prevention and treatment of anemia.Methods 80 children with anemia(case group)and 90 health children (control group)were enrolled in the study.The blood levels of trace elements (iron,zinc,calcium,magnesium,copper)and lead were detected in all subjects,in order to analyze their correlations with anemia.Results Compared with control group,the blood levels of iron,zinc and magnesium in case group were significantly lower(P<0.05),while the blood levels of calcium and lead were significantly higher(P<0.05).The blood level of copper in case group was close to that in control group(P>0.05).With the re-duction of iron,zinc and magnesium and the rise of calcium and lead,the severity of anemia increased significantly(P<0.05). Effects of copper level on the severity of anemia was not obvious(P>0.05).The blood level of iron was positive correlated with Hb,RBC and MCH (P<0.05).The blood level of zinc was positive correlated with Hb and MCH(P<0.05).The blood level of lead was negative correlated with Hb,MCV and MCH(P<0.05).Conclusion The blood level changes of trace elements and leas effect the severity of anemia in children.It is necessary to test the blood levels of trace elements and lead.