中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
17期
132-133
,共2页
李利红%高超%王霞%周秀彦
李利紅%高超%王霞%週秀彥
리리홍%고초%왕하%주수언
肝性脊髓病%肝硬化%病理生理%临床特征%肝移植
肝性脊髓病%肝硬化%病理生理%臨床特徵%肝移植
간성척수병%간경화%병리생리%림상특정%간이식
Hepatic myelopathy%Liver cirrhosis%Pathological physiology%Clinical features%Liver transplantation
目的:研究肝性脊髓病的临床特征、治疗及预后。方法:对我国2008年1月-2013年1月国内公开发表的病例报告进行回顾分析。结果:共检索到有效病例报告36篇,病例47例,其中男44例(93.62%),女3例(6.38%),年龄17~69岁。病因中前三位是乙肝肝硬化、酒精性肝硬化和丙肝肝硬化,分别有32例(68.08%)、4例(8.51%)和3例(6.38%)。经治疗后治愈1例(2.13%)、好转10例(21.28%)、无效21例(44.68%)、加重7例(14.89%)、死亡6例(12.76%)、未说明2例(4.26%)。结论:肝性脊髓病主要好发于男性,病因中绝大多数为肝硬化,其中以乙肝肝硬化为主,其次为酒精性肝硬化、丙肝肝硬化。临床表现为慢性进行性双下肢痉挛性瘫痪,内科治疗效果欠佳,肝移植为该病的最佳选择,本病多数预后不良,最终导致截瘫甚至死亡。
目的:研究肝性脊髓病的臨床特徵、治療及預後。方法:對我國2008年1月-2013年1月國內公開髮錶的病例報告進行迴顧分析。結果:共檢索到有效病例報告36篇,病例47例,其中男44例(93.62%),女3例(6.38%),年齡17~69歲。病因中前三位是乙肝肝硬化、酒精性肝硬化和丙肝肝硬化,分彆有32例(68.08%)、4例(8.51%)和3例(6.38%)。經治療後治愈1例(2.13%)、好轉10例(21.28%)、無效21例(44.68%)、加重7例(14.89%)、死亡6例(12.76%)、未說明2例(4.26%)。結論:肝性脊髓病主要好髮于男性,病因中絕大多數為肝硬化,其中以乙肝肝硬化為主,其次為酒精性肝硬化、丙肝肝硬化。臨床錶現為慢性進行性雙下肢痙攣性癱瘓,內科治療效果欠佳,肝移植為該病的最佳選擇,本病多數預後不良,最終導緻截癱甚至死亡。
목적:연구간성척수병적림상특정、치료급예후。방법:대아국2008년1월-2013년1월국내공개발표적병례보고진행회고분석。결과:공검색도유효병례보고36편,병례47례,기중남44례(93.62%),녀3례(6.38%),년령17~69세。병인중전삼위시을간간경화、주정성간경화화병간간경화,분별유32례(68.08%)、4례(8.51%)화3례(6.38%)。경치료후치유1례(2.13%)、호전10례(21.28%)、무효21례(44.68%)、가중7례(14.89%)、사망6례(12.76%)、미설명2례(4.26%)。결론:간성척수병주요호발우남성,병인중절대다수위간경화,기중이을간간경화위주,기차위주정성간경화、병간간경화。림상표현위만성진행성쌍하지경련성탄탄,내과치료효과흠가,간이식위해병적최가선택,본병다수예후불량,최종도치절탄심지사망。
Objective: To explore the clinical characteristics, treatment and prognosis of hepatic myelopathy (HM).Method: The domestic cases of HM published from January of 2008 to January of 2013 in our country were retrospectively analyzed.Result: A total of 36 effective case reports and 47 cases were found, of whom 44 cases (93.62%) were men and 3 cases (6.38%) were women. The age of them was from 17 to 69.The cause of the top three respectively were hepatitis B cirrhosis, alcoholic cirrhosis of liver and hepatitis C cirrhosis of the liver. The cases of them were 32 cases (68.08%), 4 cases (8.51%) and 3 cases (6.38%). After treatment 1 cases (2.13%) were cured, improved 10 cases (21.28%), and not improved 21 cases (44.68%), 7 cases (14.89%) aggravated, 6 cases (12.76%) died, and 2 cases (4.26%) did not explain.Conclusion: Hepatic myelopathy mainly occurs in men, and hepatitis B cirrhosis is the main reason, followed by alcoholic liver cirrhosis and hepatitis C cirrhosis of the liver. The clinical manifestations of HM is chronic progressive spastic paraparesis. The medical treatment has poor effect. Liver transplantation is the best choice for the disease, most patients have poor prognosis. HM eventually result in paraplegia and even death.