中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
17期
24-25,26
,共3页
丙泊酚%舒芬太尼%靶控输注%心脏手术
丙泊酚%舒芬太尼%靶控輸註%心髒手術
병박분%서분태니%파공수주%심장수술
Propofol%Sufentanil%Target controlled infusion%Cardiac surgery
目的：观察丙泊酚联合舒芬太尼靶控输注维持麻醉在心脏手术中的临床效果。方法：选择2010年1月-2012年6月在笔者所在医院择期行心脏手术患者46例，随机分为两组，每组23例。观察组采用靶控输注方式，对照组采用恒速泵注方式。观察记录入室(T1)、诱导即刻(T2)、插管即刻(T3)、劈胸骨(T4)、关胸骨(T5)时心率、平均动脉压的数值变化，术后清醒时间、拔管时间、ICU停留时间及术后住院时间，并对其做统计学分析。结果：在时间点T1、T2、T5上心率比较差异无统计学意义(P>0.05)；在时间点T3、T4上观察组的平均心率分别为(64.4±11.7)次/min和(68.2±9.2)次/min，较对照组低，且差异有统计学意义(P<0.05)。在时间点T1、T2、T5上平均动脉压比较差异无统计学意义(P>0.05)；在时间点T3、T4上观察组的平均动脉压分别为(76.9±11.5)mm Hg和(78.1±11.7)mm Hg，较对照组低，且差异有统计学意义(P<0.05)。与对照组比较，观察组拔管时间和ICU停留时间明显缩短，差异有统计学意义(P<0.05)。结论：麻醉诱导到维持过程中血流动力学的变化，丙泊酚联合舒芬太尼靶控输注较恒速泵注更加平稳，值得推广。
目的：觀察丙泊酚聯閤舒芬太尼靶控輸註維持痳醉在心髒手術中的臨床效果。方法：選擇2010年1月-2012年6月在筆者所在醫院擇期行心髒手術患者46例，隨機分為兩組，每組23例。觀察組採用靶控輸註方式，對照組採用恆速泵註方式。觀察記錄入室(T1)、誘導即刻(T2)、插管即刻(T3)、劈胸骨(T4)、關胸骨(T5)時心率、平均動脈壓的數值變化，術後清醒時間、拔管時間、ICU停留時間及術後住院時間，併對其做統計學分析。結果：在時間點T1、T2、T5上心率比較差異無統計學意義(P>0.05)；在時間點T3、T4上觀察組的平均心率分彆為(64.4±11.7)次/min和(68.2±9.2)次/min，較對照組低，且差異有統計學意義(P<0.05)。在時間點T1、T2、T5上平均動脈壓比較差異無統計學意義(P>0.05)；在時間點T3、T4上觀察組的平均動脈壓分彆為(76.9±11.5)mm Hg和(78.1±11.7)mm Hg，較對照組低，且差異有統計學意義(P<0.05)。與對照組比較，觀察組拔管時間和ICU停留時間明顯縮短，差異有統計學意義(P<0.05)。結論：痳醉誘導到維持過程中血流動力學的變化，丙泊酚聯閤舒芬太尼靶控輸註較恆速泵註更加平穩，值得推廣。
목적：관찰병박분연합서분태니파공수주유지마취재심장수술중적림상효과。방법：선택2010년1월-2012년6월재필자소재의원택기행심장수술환자46례，수궤분위량조，매조23례。관찰조채용파공수주방식，대조조채용항속빙주방식。관찰기록입실(T1)、유도즉각(T2)、삽관즉각(T3)、벽흉골(T4)、관흉골(T5)시심솔、평균동맥압적수치변화，술후청성시간、발관시간、ICU정류시간급술후주원시간，병대기주통계학분석。결과：재시간점T1、T2、T5상심솔비교차이무통계학의의(P>0.05)；재시간점T3、T4상관찰조적평균심솔분별위(64.4±11.7)차/min화(68.2±9.2)차/min，교대조조저，차차이유통계학의의(P<0.05)。재시간점T1、T2、T5상평균동맥압비교차이무통계학의의(P>0.05)；재시간점T3、T4상관찰조적평균동맥압분별위(76.9±11.5)mm Hg화(78.1±11.7)mm Hg，교대조조저，차차이유통계학의의(P<0.05)。여대조조비교，관찰조발관시간화ICU정류시간명현축단，차이유통계학의의(P<0.05)。결론：마취유도도유지과정중혈류동역학적변화，병박분연합서분태니파공수주교항속빙주경가평은，치득추엄。
Objective:To observe the clinical effects of target-controlled infusion of Propofol combined with Sufentanil for maintain anesthesia in cardiac surgery.Method:46 cases underwent heart surgery from January 2010 to June 2012 were divided into the observation group(23 cases) and control group(23 cases), by random number table.In the observation group,general anesthesia were induced and maintained by target-controlled infusion of Sufentanil and Propofol,in the control group,anaesthesia was managed with Propofol by a continuous infusion and Sufentanil intravenously after induction.Heart rate,mean arterial blood pressure values change at operating room(T1),induced immediate(T2),intubation (T3),sternotomy(T4),off the sternum(T5) were analysed.Result:About heart rates at T1,T2,T5,there were not statistically significant(P>0.05).Average heart rates at T3,T4 in the observation group were (64.4±11.7) bpm and 68.2±9.2)bpm,these were lower than those in the control group,there were statistically significant (P<0.05).About mean arterial pressure at T1,T2,T5,there were not statistically significant(P>0.05).Mean arterial blood pressure at T3,T4 in the observation group were (76.9±11.5)mm Hg and (78.1±11.7)mm Hg,these were lower than those in the control group,and there were statistically significant(P<0.05).Compared with control group,observation group showed earlier tracheal decannulation,shorter ICU stay length(P<0.05).Conclusion:Considering about the blood pressure and heart rate changes during anesthesia,Propofol combined with Sufentanil for target controlled infusion is more excellent in cardiac surgery,is worthy of application.
