中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
17期
110-112
,共3页
小儿过敏性紫癜%加味玉屏风散%中西医结合%临床分析
小兒過敏性紫癜%加味玉屏風散%中西醫結閤%臨床分析
소인과민성자전%가미옥병풍산%중서의결합%림상분석
Children allergic purpura%Modified Yupingfeng San%Integrated traditional Chinese and Western medicine%Clinical analysis
目的：探讨中西医结合治疗儿童过敏性紫癜（HSP）的临床效果。方法：选取2010年3月-2014年3月本院收治的90例确诊为HSP的患儿，按随机数字表法分为观察组46例和对照组44例，对照组行常规西医治疗，观察组在对照组基础上加用加味玉屏风散治疗。对比两组患儿的临床疗效及IL-5和IL-10水平。结果：观察组总有效率为95.7%，治愈率为82.6%，住院时间为（7.5±1.5）d；对照组分别为77.3%、50.0%、（8.5±2.1）d。两组上述指标比较差异均有统计学意义（P<0.05）。治疗3个月后两组的血清IL-5水活性水平明显下降，IL-10活性水平明显上升，且观察组较对照组下降或上升更明显，差异均有统计学意义（P<0.05）。结论：中西医结合的综合疗法治疗HSP可显著提高患儿的治愈率和有效率，缩短病程，提高患儿的生命质量，可进一步推广应用。
目的：探討中西醫結閤治療兒童過敏性紫癜（HSP）的臨床效果。方法：選取2010年3月-2014年3月本院收治的90例確診為HSP的患兒，按隨機數字錶法分為觀察組46例和對照組44例，對照組行常規西醫治療，觀察組在對照組基礎上加用加味玉屏風散治療。對比兩組患兒的臨床療效及IL-5和IL-10水平。結果：觀察組總有效率為95.7%，治愈率為82.6%，住院時間為（7.5±1.5）d；對照組分彆為77.3%、50.0%、（8.5±2.1）d。兩組上述指標比較差異均有統計學意義（P<0.05）。治療3箇月後兩組的血清IL-5水活性水平明顯下降，IL-10活性水平明顯上升，且觀察組較對照組下降或上升更明顯，差異均有統計學意義（P<0.05）。結論：中西醫結閤的綜閤療法治療HSP可顯著提高患兒的治愈率和有效率，縮短病程，提高患兒的生命質量，可進一步推廣應用。
목적：탐토중서의결합치료인동과민성자전（HSP）적림상효과。방법：선취2010년3월-2014년3월본원수치적90례학진위HSP적환인，안수궤수자표법분위관찰조46례화대조조44례，대조조행상규서의치료，관찰조재대조조기출상가용가미옥병풍산치료。대비량조환인적림상료효급IL-5화IL-10수평。결과：관찰조총유효솔위95.7%，치유솔위82.6%，주원시간위（7.5±1.5）d；대조조분별위77.3%、50.0%、（8.5±2.1）d。량조상술지표비교차이균유통계학의의（P<0.05）。치료3개월후량조적혈청IL-5수활성수평명현하강，IL-10활성수평명현상승，차관찰조교대조조하강혹상승경명현，차이균유통계학의의（P<0.05）。결론：중서의결합적종합요법치료HSP가현저제고환인적치유솔화유효솔，축단병정，제고환인적생명질량，가진일보추엄응용。
Objective:To investigate the clinical effect of the combination of traditional Chinese and Western medicine treatment on children with allergic purpura(HSP).Method:90 patients with HSP in our hospital from March 2010 to March 2014 were selected,and randomly divided into 46 cases in the observation group and 44 cases in the control group,the control group were given conventional western medicine treatment,based on the control group,the observation group were given modified Yupingfeng San treatment,the clinical curative effect and the IL-5 and IL-10 levels two groups were compared.Result:In the observation group,the total effectiveness was 95.7%,the cure rate was 82.6%,hospitalization time was(7.5±1.5)d;in the control group respectively were 77.3%,50.0%,(8.5±2.1)d. The differences of above indicators between the two groups had statistically significant(P<0.05). After 3 months treatment, the serum IL-5 activity significantly decreased,IL-10 activity significantly increased,and the observation group decreased or increased more significantly than in the control group,there were statistically significant differences(P<0.05). Conclusion:Combined therapy of Chinese and Western medicine to treat allergic purpura can significantly improve the cure rate and efficiency of children,shorten the course of disease,improve the quality of life in children,can be further applied.
