CAJ | 학술논문

目的：观察间断和“持续”血液灌流对急性百草枯中毒患者的临床疗效。方法：回顾性研究本院急性百草枯中毒患者59例，所有患者均采用内科常规综合治疗，分为A组26例采用间断血液灌流，B组33例采用“持续”血液灌流，根据患者预后又分为死亡组和存活组。结果：A、B两组患者性别、年龄、服药剂量、服药后至入院治疗时间比较差异无统计学意义（P>0.05）；A、B两组患者治疗疗效比较差异无统计学意义（P>0.05），B组死亡患者存活时间长于A组（P<0.05）；与存活组相比，死亡组服药剂量明显增高。结论：间断和“持续”血液灌流对于百草枯中毒患者疗效相同，“持续”血液灌流能明显延长中毒死亡患者的存活时间，中毒患者死亡因素主要与患者服用百草枯剂量有关。
목적：관찰간단화“지속”혈액관류대급성백초고중독환자적림상료효。방법：회고성연구본원급성백초고중독환자59례，소유환자균채용내과상규종합치료，분위A조26례채용간단혈액관류，B조33례채용“지속”혈액관류，근거환자예후우분위사망조화존활조。결과：A、B량조환자성별、년령、복약제량、복약후지입원치료시간비교차이무통계학의의（P>0.05）；A、B량조환자치료료효비교차이무통계학의의（P>0.05），B조사망환자존활시간장우A조（P<0.05）；여존활조상비，사망조복약제량명현증고。결론：간단화“지속”혈액관류대우백초고중독환자료효상동，“지속”혈액관류능명현연장중독사망환자적존활시간，중독환자사망인소주요여환자복용백초고제량유관。
Objective:To assess the clinical effects of intermittent and continuous hemoperfusion on acute paraquat poisoning. Method:59 patients with acute paraquat poisoning were randomly divided into two groups,A group composed of 26 patients were treated with intermittent hemoperfusion and continuous hemoperfusion was administered in B group composed of 33 patients. All patients were treated with conventional medication. then,According to the prognosis of the patients was divided into death group and survival group. Result:There were no significant difference in Gender, age,the toxic dose,and after the poisoning to hospitalization time between the two groups(P>0.05). Therapeutic effect of the A and B group had no difference(P>0.05). The survival time of death patients in the B group was longer than that of death patients in the A group(P<0.05). Compared with the survival group,the toxic dose was higher significantly in death group. Conclusion:There is no difference in the clinical efficacy between intermittent and continuous hemoperfusion on acute paraquat poisoning,continuous hemoperfusion can prolong the survival time of death obviously,the main causes of death is related to the toxic dose.