中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
17期
18-20,21
,共4页
激素%皮质醇%感染性休克
激素%皮質醇%感染性休剋
격소%피질순%감염성휴극
Corticosteroid%Cortisol%Septic shock
目的：研究激素治疗对于感染性休克患者的预后及并发症的影响。方法：回顾性收集重症监护病房（ICU）的177例感染性休克患者的病例资料，根据是否应用激素治疗分为激素治疗组78例和非激素治疗组99例。统计分析两组患者的危重程度、预后和并发症等指标。结果：（1）激素治疗组的皮质醇水平为（17.8±14.1）μg/dL，低于非激素治疗组的（26.8±15.5）μg/dL，两组比较差异有统计学意义（P<0.05）；（2）激素治疗组的院内感染发生率、7 d休克逆转率、28 d生存率分别为51.3%、57.7%、71.8%，与非激素治疗组比较差异均有统计学意义（P<0.05）；（3）两组的平均血糖比较差异无统计学意义（P>0.05）。结论：激素治疗能明显提高患者的7 d休克逆转率和28 d生存率，也提高了院内感染的发生率，但激素治疗并不能引发高血糖反应。
目的：研究激素治療對于感染性休剋患者的預後及併髮癥的影響。方法：迴顧性收集重癥鑑護病房（ICU）的177例感染性休剋患者的病例資料，根據是否應用激素治療分為激素治療組78例和非激素治療組99例。統計分析兩組患者的危重程度、預後和併髮癥等指標。結果：（1）激素治療組的皮質醇水平為（17.8±14.1）μg/dL，低于非激素治療組的（26.8±15.5）μg/dL，兩組比較差異有統計學意義（P<0.05）；（2）激素治療組的院內感染髮生率、7 d休剋逆轉率、28 d生存率分彆為51.3%、57.7%、71.8%，與非激素治療組比較差異均有統計學意義（P<0.05）；（3）兩組的平均血糖比較差異無統計學意義（P>0.05）。結論：激素治療能明顯提高患者的7 d休剋逆轉率和28 d生存率，也提高瞭院內感染的髮生率，但激素治療併不能引髮高血糖反應。
목적：연구격소치료대우감염성휴극환자적예후급병발증적영향。방법：회고성수집중증감호병방（ICU）적177례감염성휴극환자적병례자료，근거시부응용격소치료분위격소치료조78례화비격소치료조99례。통계분석량조환자적위중정도、예후화병발증등지표。결과：（1）격소치료조적피질순수평위（17.8±14.1）μg/dL，저우비격소치료조적（26.8±15.5）μg/dL，량조비교차이유통계학의의（P<0.05）；（2）격소치료조적원내감염발생솔、7 d휴극역전솔、28 d생존솔분별위51.3%、57.7%、71.8%，여비격소치료조비교차이균유통계학의의（P<0.05）；（3）량조적평균혈당비교차이무통계학의의（P>0.05）。결론：격소치료능명현제고환자적7 d휴극역전솔화28 d생존솔，야제고료원내감염적발생솔，단격소치료병불능인발고혈당반응。
Objective:To observe corticosteroid therapy for patients with septic shock and complications affecting prognosis.Method:The clinical data of 177 patients with septic shock in the Intensive Care Unit(ICU)were retrospectively collected,according to whether corticosteroid therapy divided into the corticosteroid therapy group (n=78)and the non-corticosteroid therapy group(n=99). The critical degree,prognosis and complications indicators between the two groups were statistical analyzed.Result:(1)The cortisol level of the corticosteroid therapy group was (17.8±14.1)μg/dL,and lower than(26.8±15.5)μg/dL in the non-corticosteroid therapy group,the difference was statistically significant(P<0.05).(2)The hospital infection rate,7 days shock reversal rate,28 days survival rates of the corticosteroid therapy group were 51.3%,57.7%,71.8%,and compared with the non-corticosteroid treatment group,the differences were statistically significant(P<0.05).(3)The difference of glucose of the two groups had no statistical significance(P>0.05).Conclusion:The corticosteroid therapy can significantly improve patients’the 7 days shock transfer rates and 28 days survival rates,at the same time can increase the incidence of nosocomial infections,but corticosteroid therapy is not able to trigger high blood sugar response.
