CAJ | 학술논문

目的：分析颈动脉粥样硬化（CAS）斑块及危险因素与脑梗死的相关性。方法应用回顾性分析的方法，以宝钛集团有限公司职工医院80例确诊的脑梗死患者为病例组，同期检查的76例非脑梗死患者为对照组，2组年龄及性别构成无显著差异。所有患者均行颈动脉彩色多普勒超声检查,对2组患者的高血压病史、糖尿病史、甘油三酯（TG）、总胆固醇/高密度脂蛋白（TC/HDL-C）比值、低密度脂蛋白（LDL-C）等进行比较，并对影响颈动脉粥样板块及脑梗死的危险因素进行Logistic多因素回归分析。结果脑梗死组颈动脉粥样斑块、高血压、血脂异常及糖尿病的发生率明显高于对照组（P<0.01）。Logistic回归分析显示，影响脑梗死的危险因素为颈动脉粥样硬化、高血压、糖尿病、TC/HDL-C比值、LDL-C（P<0.05）。结论颈动脉粥样斑块与脑梗死的发生密切相关，颈部血管彩色多谱勒超声检测对预测和治疗脑梗死有重要意义，多种危险因素影响脑梗死及颈动脉粥样斑块的形成。
목적：분석경동맥죽양경화（CAS）반괴급위험인소여뇌경사적상관성。방법응용회고성분석적방법，이보태집단유한공사직공의원80례학진적뇌경사환자위병례조，동기검사적76례비뇌경사환자위대조조，2조년령급성별구성무현저차이。소유환자균행경동맥채색다보륵초성검사,대2조환자적고혈압병사、당뇨병사、감유삼지（TG）、총담고순/고밀도지단백（TC/HDL-C）비치、저밀도지단백（LDL-C）등진행비교，병대영향경동맥죽양판괴급뇌경사적위험인소진행Logistic다인소회귀분석。결과뇌경사조경동맥죽양반괴、고혈압、혈지이상급당뇨병적발생솔명현고우대조조（P<0.01）。Logistic회귀분석현시，영향뇌경사적위험인소위경동맥죽양경화、고혈압、당뇨병、TC/HDL-C비치、LDL-C（P<0.05）。결론경동맥죽양반괴여뇌경사적발생밀절상관，경부혈관채색다보륵초성검측대예측화치료뇌경사유중요의의，다충위험인소영향뇌경사급경동맥죽양반괴적형성。
Objective Analysis of carotid atherosclerotic plaque and the correleation between risk factors and cerebral infarction. Methods Retrospective analysis method is applied to 80 cases for diagnosis of cerebral infarction patients group, 76 cases of cerebral infarction were examined by the same period as the control group ,two groups of age and gender had no significant difference. All patients were performed carotid artery color Doppler ultrasound exameination, the two groups of patients with hypertension, diabetes, triglyceride(TG),total colesterolhd/high-density lipoprotein cholesterol(TC/HDL-C)ratio, low density lipoprotein cholesterol (LDL-C),such as comparison ,and the effect of carotid atherosclerotic plaque and cerebral infarction risk factors for Logistic multifactor regression analysis. Results Cerebral infarction group of carotid artery atheromatous plaque and the incidence of hypertension, diabetes and dyslipidemia is significantly higher than the control group(P<0.05). Logistic regression analysis showed that the impact of cerebral infarction risk factors for carotid atherosclerosis, hypertension, diabetes, TC and TC/HDL-C ratio(P<0.05). Conclusion Carotid atherosclerosis and cerebral infarction is closely related to the occurrence, neck vessels of color Doppler ultrasound has important significance for the prediction and treatment of cerebral infarction, multiple risk factors influencing the formation of carotid artery atherosclerotic plaque.