中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
26期
4158-4162
,共5页
佘远时%陈广祥%陈广东%王以进%邹天明
佘遠時%陳廣祥%陳廣東%王以進%鄒天明
사원시%진엄상%진엄동%왕이진%추천명
植入物%骨植入物%可灌注动力髋螺钉%骨水泥%骨质疏松%股骨转子间骨折
植入物%骨植入物%可灌註動力髖螺釘%骨水泥%骨質疏鬆%股骨轉子間骨摺
식입물%골식입물%가관주동력관라정%골수니%골질소송%고골전자간골절
internal fixators%osteoporotic fractures%biomechanics
背景:动力髋螺钉内固定系统被认为是治疗股骨转子间骨折的经典方法,但髋螺钉切割股骨头后位置偏移是目前常见的力学失败,需要进行二次手术。目的:在传统动力髋螺钉内固定系统的基础上,对髋螺钉部分进行改良,设计可灌注骨水泥动力髋螺钉内固定系统,探讨其治疗骨质疏松股骨转子间骨折的可行性及生物力学性能。方法:取24具新鲜完整湿润的人骨质疏松髋部标本,测量骨密度,按标准制成AO31-A1型股骨转子间骨折模型,每份骨质疏松髋部标本,其中一侧置入可灌注骨水泥动力髋螺钉内固定系统作为实验组,另一侧置入传统动力髋螺钉内固定系统作为对照组,进行轴向压缩、扭转度及失效载荷生物力学测试,比较两者生物力学性能。结果与结论:实验组应力强度、轴向刚度、水平剪切刚度高于对照组(P<0.05);当扭角为3°时,实验组扭矩高于对照组(P <0.05);实验组失效载荷高于对照组(P <0.05)。表明可灌注骨水泥动力髋螺钉内固定系统治疗老年骨质疏松股骨转子间骨折,能有效增强髋螺钉的把持力,防止股骨头切割,其生物力学强度、刚度、抗疲劳性及稳定性均强于传统动力髋螺钉。
揹景:動力髖螺釘內固定繫統被認為是治療股骨轉子間骨摺的經典方法,但髖螺釘切割股骨頭後位置偏移是目前常見的力學失敗,需要進行二次手術。目的:在傳統動力髖螺釘內固定繫統的基礎上,對髖螺釘部分進行改良,設計可灌註骨水泥動力髖螺釘內固定繫統,探討其治療骨質疏鬆股骨轉子間骨摺的可行性及生物力學性能。方法:取24具新鮮完整濕潤的人骨質疏鬆髖部標本,測量骨密度,按標準製成AO31-A1型股骨轉子間骨摺模型,每份骨質疏鬆髖部標本,其中一側置入可灌註骨水泥動力髖螺釘內固定繫統作為實驗組,另一側置入傳統動力髖螺釘內固定繫統作為對照組,進行軸嚮壓縮、扭轉度及失效載荷生物力學測試,比較兩者生物力學性能。結果與結論:實驗組應力彊度、軸嚮剛度、水平剪切剛度高于對照組(P<0.05);噹扭角為3°時,實驗組扭矩高于對照組(P <0.05);實驗組失效載荷高于對照組(P <0.05)。錶明可灌註骨水泥動力髖螺釘內固定繫統治療老年骨質疏鬆股骨轉子間骨摺,能有效增彊髖螺釘的把持力,防止股骨頭切割,其生物力學彊度、剛度、抗疲勞性及穩定性均彊于傳統動力髖螺釘。
배경:동력관라정내고정계통피인위시치료고골전자간골절적경전방법,단관라정절할고골두후위치편이시목전상견적역학실패,수요진행이차수술。목적:재전통동력관라정내고정계통적기출상,대관라정부분진행개량,설계가관주골수니동력관라정내고정계통,탐토기치료골질소송고골전자간골절적가행성급생물역학성능。방법:취24구신선완정습윤적인골질소송관부표본,측량골밀도,안표준제성AO31-A1형고골전자간골절모형,매빈골질소송관부표본,기중일측치입가관주골수니동력관라정내고정계통작위실험조,령일측치입전통동력관라정내고정계통작위대조조,진행축향압축、뉴전도급실효재하생물역학측시,비교량자생물역학성능。결과여결론:실험조응력강도、축향강도、수평전절강도고우대조조(P<0.05);당뉴각위3°시,실험조뉴구고우대조조(P <0.05);실험조실효재하고우대조조(P <0.05)。표명가관주골수니동력관라정내고정계통치료노년골질소송고골전자간골절,능유효증강관라정적파지력,방지고골두절할,기생물역학강도、강도、항피로성급은정성균강우전통동력관라정。
BACKGROUND:Dynamic hip screws have been considered as a classic method for intertrochanteric fracture. However, migration of the hip screw resulting in cut-out of the femoral head remains the most common mechanical failure, which requires secondary surgery. OBJECTIVE:On the basis of the traditional dynamic hip screw, we modified the lag screw, designed new internal fixation system as cemented dynamic hip screws to explore the feasibility and the biomechanical properties for the treatment of osteoporotic intertrochanteric fracture. METHODS:A total of 24 hip samples were harvested from fresh cadavers with osteoporosis. Bone density was measured. According to the standards, the specimens were made into intertrochanteric fracture models of AO31-A1 type. Of each specimen, one side implanted with cemented dynamic hip screws served as experimental group, and another side implanted with traditional dynamic hip screw served as control group. Axial compression, twisting and fatigue load biomechanics were tested. Their biomechanical functions were compared. RESULTS AND CONCLUSION:Stress intensity, axial stiffness and horizontal shear stiffness were higher in the experimental group than in the control group (P<0.05). At torsion angle of 3°, torsional moment was higher in the experimental group than in the control group (P<0.05). Fatigue load was higher in the experimental group than in the control group (P<0.05). Results suggested that cemented dynamic hip screw internal fixation system in the treatment of senile osteoporotic intertrochanteric fracture can effectively enhance the hip screw holding force and prevent femoral cutting. Biomechanical property, stiffness, endurance resistance and stability of cemented dynamic hip screw are better than traditional dynamic hip screw.