农垦医学
農墾醫學
농은의학
AGRICULTURAL RECLAMATION MEDICINE
2014年
1期
62-64,65
,共4页
孕产妇%妇产科%超说明书用药
孕產婦%婦產科%超說明書用藥
잉산부%부산과%초설명서용약
Pregnant and Parturient Women%Obstetrics and Gynecology Ward%Off-label Drug Use
目的：回顾性调查石河子大学医学院第一附属医院住院孕产妇超说明书用药情况，及时反馈临床以促进本院孕产妇合理用药。方法：收集本院2013年1月1日至10月31日妇产科住院孕产妇的用药医嘱，依据药品说明书，分别对医嘱中的适应证、人群适宜性、给药剂量、频次、溶媒等方面进行系统分析。结果：共抽取住院孕产妇1026例，分析用药医嘱17407条，涉及药品147种；按照患者、用药医嘱和药品计，超说明书发生率分别为68．42％、10．59％和8．84％。超说明书用药类型中超用法、用量所占比例最大，达到了62．73％。排名前4位的超说明书用药种类依次为激素及其有关药物（35．53％）、呼吸系统药物（28．05％）、血液及造血系统药物（24．78％）和调节水、电解质和酸碱平衡药物（23．35％）。结论：通过本文的调查，发现本院的住院孕产妇超说明书用药的现象时有发生。建议医生临床用药时注意权衡利弊，尽量按照药品说明书中规定的要求使用药物。确有需要超说明书用药时应以充分的循证医学证据支持为前提，从而避免医疗纠纷和执业风险。
目的：迴顧性調查石河子大學醫學院第一附屬醫院住院孕產婦超說明書用藥情況，及時反饋臨床以促進本院孕產婦閤理用藥。方法：收集本院2013年1月1日至10月31日婦產科住院孕產婦的用藥醫囑，依據藥品說明書，分彆對醫囑中的適應證、人群適宜性、給藥劑量、頻次、溶媒等方麵進行繫統分析。結果：共抽取住院孕產婦1026例，分析用藥醫囑17407條，涉及藥品147種；按照患者、用藥醫囑和藥品計，超說明書髮生率分彆為68．42％、10．59％和8．84％。超說明書用藥類型中超用法、用量所佔比例最大，達到瞭62．73％。排名前4位的超說明書用藥種類依次為激素及其有關藥物（35．53％）、呼吸繫統藥物（28．05％）、血液及造血繫統藥物（24．78％）和調節水、電解質和痠堿平衡藥物（23．35％）。結論：通過本文的調查，髮現本院的住院孕產婦超說明書用藥的現象時有髮生。建議醫生臨床用藥時註意權衡利弊，儘量按照藥品說明書中規定的要求使用藥物。確有需要超說明書用藥時應以充分的循證醫學證據支持為前提，從而避免醫療糾紛和執業風險。
목적：회고성조사석하자대학의학원제일부속의원주원잉산부초설명서용약정황，급시반궤림상이촉진본원잉산부합리용약。방법：수집본원2013년1월1일지10월31일부산과주원잉산부적용약의촉，의거약품설명서，분별대의촉중적괄응증、인군괄의성、급약제량、빈차、용매등방면진행계통분석。결과：공추취주원잉산부1026례，분석용약의촉17407조，섭급약품147충；안조환자、용약의촉화약품계，초설명서발생솔분별위68．42％、10．59％화8．84％。초설명서용약류형중초용법、용량소점비례최대，체도료62．73％。배명전4위적초설명서용약충류의차위격소급기유관약물（35．53％）、호흡계통약물（28．05％）、혈액급조혈계통약물（24．78％）화조절수、전해질화산감평형약물（23．35％）。결론：통과본문적조사，발현본원적주원잉산부초설명서용약적현상시유발생。건의의생림상용약시주의권형리폐，진량안조약품설명서중규정적요구사용약물。학유수요초설명서용약시응이충분적순증의학증거지지위전제，종이피면의료규분화집업풍험。
Objective:To determine the extent of off-label drug use in obstetrics and gynecology ward of Shihezi Uni-versity hospital from January 1,2013 to October 31,2013,In order to promote rational drug use in pregnant and parturient women.Methods:Collected from January 1,2013 to October 31 in the hospital of obstetrics and Gynecology ward medicationorders,based on the drug package insert,indications on doctor's orders,respectively,groups of suitability,dose,frequency,solvent for analysis,determine whether its Off-label Drug Use as well as Off-label Drug Use types and analysis of key hyper -Manual of evidence-based medicine proofs.Results:The total 1026 pregnant and parturient women were selected ,and 17407The rate of off-label drug use was 68.42%,10.59% and 8.84% in pregnant and parturient women,medication orders anddrug categories,respectively.prescriptions involving 147 drugs were analyzed.Off-label Drug Use the largest proportion typeSuper-usage,dosage,reached a total of 62.73%.The top four Types of drugs off-label drug use is Regulation of water ,electrolyteand acid-base balance of drugs,hormones and related drugs,central nervous system drugs and blood and blood-formingsystem drugs.Conclusion:The off-label drug use in obstetrics and gynecology ward is common in Shihezi UniversityHospital and Most of which are supported by Clinical evidence ;But due to lack of evidence of more authoritative evidence -based medicine.So the doctor for pregnant and parturient women clinical off -label drug should be weighed.
