CAJ | 학술논문

肺良性转移性平滑肌瘤（pulmonary benign metastasizing leiomyoma, PBML）是一种罕见疾病，临床工作中易被误诊。本文拟探讨PBML的临床病理学特征、诊断、治疗及预后。回顾性分析5例PBML患者的临床资料和病理学特点。患者均为女性，平均年龄46.8岁。肺转移瘤发生在诊断子宫平滑肌瘤后89个月-226个月。4例为肺内多发性结节，1例为单发性，1例伴左肾转移。手术方式包括3例胸腔镜下楔形切除，1例左肺上叶切除，1例右肺上叶切除+右肺中叶、下叶楔形切除。术后随访3个月-48个月，肺内残余病灶无进展。PBML主要发生于有子宫平滑肌瘤病史的女性。肺是最主要的转移部位。手术切除是主要的治疗手段。肿瘤激素依赖性，可予内分泌治疗。
폐량성전이성평활기류（pulmonary benign metastasizing leiomyoma, PBML）시일충한견질병，림상공작중역피오진。본문의탐토PBML적림상병이학특정、진단、치료급예후。회고성분석5례PBML환자적림상자료화병이학특점。환자균위녀성，평균년령46.8세。폐전이류발생재진단자궁평활기류후89개월-226개월。4례위폐내다발성결절，1례위단발성，1례반좌신전이。수술방식포괄3례흉강경하설형절제，1례좌폐상협절제，1례우폐상협절제+우폐중협、하협설형절제。술후수방3개월-48개월，폐내잔여병조무진전。PBML주요발생우유자궁평활기류병사적녀성。폐시최주요적전이부위。수술절제시주요적치료수단。종류격소의뢰성，가여내분비치료。
Pulmonary benign metastasizing leiomyoma (PBML) is a rare and otfen to be misdiagnosed disease. In this study, we want to investigate the diseased of the clinicopathological characteristics, diagnosis, treatment and prognosis. hTe retrospective analysis were performed on the clinicopathological data of 5 patients with PBML. All 5 cases were female, mean age 46.8 years old, and were found with single nodule. One case was found with letf kidney metastasis. Surgical procedures in-cludes:VATS biopsy (3 cases), resection of superior lobe of letf lung (1 case), resection of superior lobe of right lung and wedge resection of middle and inferior lobe of right lung (1 case). hTe residual nodules in lung were stable in all cases with followup 3-48 mo. PBML is dominated occurring in females with history of uterine leiomyoma, preferential to metastasize to lung, and surgery is the primary therapy. Since it is hormone dependent, hormonal therapy may be suggested in these patients.