CAJ | 학술논문

目的：评价 CT 引导下穿刺灌注化疗联合放疗治疗盆腔囊性恶性肿瘤的疗效,分析其安全性,探讨其临床应用价值。方法 CT 引导下经皮穿刺置管于盆腔囊性肿物内,局部灌注顺铂化疗,同步行放射治疗。对穿刺患者随访,进行疗效评价,了解并发症情况,分析临床疗效、安全性及临床应用价值。结果18例患者中一次性穿刺成功率100%。其中4周内部分缓解率为100%,局部缓解时间最短为6个月,最长为25个月,1例达完全缓解。18例患者均未出现Ⅲ度以上胃肠道不良反应、骨髓抑制等。整个手术操作时间20~42 min,平均24 min,未出现感染、出血、穿孔等并发症。结论 CT 引导下穿刺灌注化疗联合放疗治疗盆腔囊性恶性肿瘤安全有效,副作用较小,值得推广。
목적：평개 CT 인도하천자관주화료연합방료치료분강낭성악성종류적료효,분석기안전성,탐토기림상응용개치。방법 CT 인도하경피천자치관우분강낭성종물내,국부관주순박화료,동보행방사치료。대천자환자수방,진행료효평개,료해병발증정황,분석림상료효、안전성급림상응용개치。결과18례환자중일차성천자성공솔100%。기중4주내부분완해솔위100%,국부완해시간최단위6개월,최장위25개월,1례체완전완해。18례환자균미출현Ⅲ도이상위장도불량반응、골수억제등。정개수술조작시간20~42 min,평균24 min,미출현감염、출혈、천공등병발증。결론 CT 인도하천자관주화료연합방료치료분강낭성악성종류안전유효,부작용교소,치득추엄。
Objective To evaluate the efficacy and safety of CT-guided puncture and intracapsular perfusion of chemotherapeutic drugs combining with radiotherapy on pelvic cystic malignancies.Methods Cisplatin was infused into the tumor through the percuta-neous catheter under the CT guidance.At the same time the radiation therapy was performed.During the follow-up,the patient’s complications,clinical efficacy,safety and clinical application value were evaluated.Results All 18 patients were punctured success-fully for the first time with an accuracy rate 100%.After treatment for 4 weeks,all patients were responded to the treatment with a partial response rate 100%.The duration of partial response ranged from 6 to 25 months.One patient was completely responded. Severe gastrointestinal adverse reactions and bone marrow suppression were not found in all patients.The duration of the puncture procedure ranged from 20 to 42 minutes with an average duration 24 min,and no complications such as infection,bleeding and perfo-ration were found.Conclusion The treatment of intracapsular perfusion of chemotherapeutic drugs combining with radiotherapy un-der CT-guided puncture on cystic pelvic malignancies is effective and safe with fewer adverse reactions.