CAJ | 학술논문

目的：探讨320排螺旋 CT 心肌灌注技术在冠心病心功能评价的应用价值。方法回顾性分析24例存在可逆性心肌缺血的冠心病患者及13例正常志愿者，进行320排螺旋 CT 静息及多巴酚丁胺负荷心肌灌注扫描，测量静息、多巴酚丁胺负荷后对应的心功能指标(ESV、EDV、SV、EF)值，对检测结果采用配对 t 检验和独立样本 t 检验分析，当 P 值<0.05时，认为差异或相关性具有统计学意义。结果正常组在静息、多巴酚丁胺负荷后心功能指标除 EF 外，其余(ESV、EDV、SV)值均有显著差异性；冠心病组除 EF 值有差异性外，其余心功能指标在静息、负荷下无显著性差异。正常组和冠心病组在静息、负荷下各对应心功能指标值均有显著差异。结论多巴酚丁胺负荷320排螺旋 CT 心肌灌注能判断缺血心肌心功能受损程度，为冠心病综合评价及预后判断提供依据。
목적：탐토320배라선 CT 심기관주기술재관심병심공능평개적응용개치。방법회고성분석24례존재가역성심기결혈적관심병환자급13례정상지원자，진행320배라선 CT 정식급다파분정알부하심기관주소묘，측량정식、다파분정알부하후대응적심공능지표(ESV、EDV、SV、EF)치，대검측결과채용배대 t 검험화독립양본 t 검험분석，당 P 치<0.05시，인위차이혹상관성구유통계학의의。결과정상조재정식、다파분정알부하후심공능지표제 EF 외，기여(ESV、EDV、SV)치균유현저차이성；관심병조제 EF 치유차이성외，기여심공능지표재정식、부하하무현저성차이。정상조화관심병조재정식、부하하각대응심공능지표치균유현저차이。결론다파분정알부하320배라선 CT 심기관주능판단결혈심기심공능수손정도，위관심병종합평개급예후판단제공의거。
Objective To explore the application value of 320-slice spiral CT myocardial perfusion technique in the evaluation of cardiac function in patients with coronary artery disease.Methods 24 patients with known reversible myocardial ischemia with coro-nary heart disease and 13 cases of normal were detected by 320-slice spiral CT myocardial perfusion scan in resting and after dobu-tamine-induced stress,measured the values of cardiac function indexes(ESV、EDV、SV、EF)in resting and after dobutamine-induced stress respectively,the results were analyzed by paired t test and independent sample t test,when the P value is less than 0.05,con-sidered statistically significant or correlation.Results The values of cardiac function indexes (ESV,EDV,SV)between the resting and after dobutamine-induced stress were significantly different except EF value in normal group.But only the EF value was signifi-cantly different in CHD,the rest values of cardiac function indexes(ESV,EDV,SV)no significant difference.Each corresponding value of cardiac function indexes in resting and after dobutamine-induced stress was significantly different between the CHD and the normal.Conclusion The dobutamine-induced stress myocardial perfusion with 320-slice spiral CT can judge the impaired degree of cardiac function in patients with myocardial ischemia,provide the basis for comprehensive evaluation of coronary artery disease and its prognosis.