CAJ | 학술논문

目的：通过动态 X 线摄影,分析正常人与阻塞性睡眠呼吸暂停综合征(OSAS)患者在清醒及睡眠状态下上气道塌陷性变化特点。方法筛选20例正常人与20例 OSAS 患者,分别在清醒和睡眠状态下行上气道动态 X 线摄影,并观察与测量上气道管径在腭咽、口咽、喉咽3个水平随呼吸运动的动态变化特点。结果正常人在睡眠状态下,腭咽部上气道塌陷度较清醒时增大(P =0.014,P <0.05),有统计学意义。口咽及喉咽部上气道塌陷度在清醒与睡眠状态下的差别无统计学意义。OSAS 患者腭咽部、口咽部、喉咽部气道塌陷度在清醒与睡眠状态下存在明显统计学差异,分别为(P =0.000,P <0.05)、(P =0.001,P <0.05)、(P =0.013, P <0.05)。清醒状态下,正常人与 OSAS 患者腭咽、口咽部、喉咽部气道塌陷度无统计学差异。在睡眠状态下,OSAS 患者腭咽部、口咽部上气道塌陷度明显高于正常人,有统计学差异(P =0.000,P <0.05),(P =0.003,P <0.05),喉咽部无统计学差异。结论正常人在睡眠状态下,上气道腭咽部塌陷度较清醒时增大,而口咽及喉咽部变化不大。OSAS 患者睡眠状态下腭咽、口咽、喉咽部气道塌陷度较清醒时明显增大,清醒状态下上气道变化不能真实反映睡眠状态下的改变。睡眠状态下 OSAS 患者上气道在腭咽及口咽部塌陷度明显高于正常人,但在清醒状态下 OSAS 患者上气道较正常人变化不大。
목적：통과동태 X 선섭영,분석정상인여조새성수면호흡잠정종합정(OSAS)환자재청성급수면상태하상기도탑함성변화특점。방법사선20례정상인여20례 OSAS 환자,분별재청성화수면상태하행상기도동태 X 선섭영,병관찰여측량상기도관경재악인、구인、후인3개수평수호흡운동적동태변화특점。결과정상인재수면상태하,악인부상기도탑함도교청성시증대(P =0.014,P <0.05),유통계학의의。구인급후인부상기도탑함도재청성여수면상태하적차별무통계학의의。OSAS 환자악인부、구인부、후인부기도탑함도재청성여수면상태하존재명현통계학차이,분별위(P =0.000,P <0.05)、(P =0.001,P <0.05)、(P =0.013, P <0.05)。청성상태하,정상인여 OSAS 환자악인、구인부、후인부기도탑함도무통계학차이。재수면상태하,OSAS 환자악인부、구인부상기도탑함도명현고우정상인,유통계학차이(P =0.000,P <0.05),(P =0.003,P <0.05),후인부무통계학차이。결론정상인재수면상태하,상기도악인부탑함도교청성시증대,이구인급후인부변화불대。OSAS 환자수면상태하악인、구인、후인부기도탑함도교청성시명현증대,청성상태하상기도변화불능진실반영수면상태하적개변。수면상태하 OSAS 환자상기도재악인급구인부탑함도명현고우정상인,단재청성상태하 OSAS 환자상기도교정상인변화불대。
Objective To analyze the difference in changes of upper airway between obstructive sleep apnea syndrome (OSAS) patients and normal population using dynamic radiography under sleeping and awake conditions.Methods 20 normal subjects and 20 OSAS patients underwent the dynamic digital radiography of the upper airway under sleeping and awake conditions.And the dynamic diameter changes of the upper airway at velopharyngeal,oropharynx and hypopharynx levels were measured and recorded.Results The velo-pharyngeal upper airway collapse in normal subjects under sleeping condition was significantly larger than that under awake condition (P <0.014).However no significant differences in the collapse of upper airway at oropharynx and hypopharynx level were observed between sleeping and awake conditions.For the OSAS patients,the upper airway collapses at velopharyngeal,oropharynx and hypopharynx levels under sleeping condition were significantly larger than those under awake condition respectively (P <0.000,P =0.001,P <0.013). During awake state,there were no significant differences in upper airway collapse at velopharyngeal,oropharynx and hypopharynx levels between normal subjects and OSAS patients under awake condition.During sleeping state,the upper airway collapses of OSAS patients were significantly larger than that of normal subjects at velopharyngeal and oropharyngeal levels (P =0.000,P =0.003). However,no significant difference was observed at hypopharynx level.Conclusion The normal upper airway represents obvious col-lapse at velopharyngeal level under sleeping condition.However,the upper airway in OSAS patients at velopharyngeal,oropharynx and hypopharynx level showed significant collapse under sleeping condition compared with that under awake condition.The upper airway of the OSAS patients represents obvious collapse at velopharyngeal and oropharyngeal level under sleeping condition,however no abnormal changes can be observed under awake condition.