CAJ | 학술논문

以二乙胺、丙烯酸甲酯为原料，经迈克尔加成，生成3-甲氧基-二乙基丙烯酸甲酯（产物Ⅰ），再与吗啉酰胺化生成3-吗啉基-二乙基丙酰胺（产物Ⅱ），最后经催化裂解得到丙烯酰吗啉。研究了投料比、反应温度、反应时间等因素对中间产物Ⅱ反应影响。结果表明，最佳反应条件为：产物Ⅰ、吗啉与甲醇钠摩尔投料比1：1.2：0.2，反应温度80~90℃，反应时间5~6 h，产物Ⅱ纯度可达82%，收率可达88%。产物Ⅱ再经催化裂解得目标产品丙烯酰吗啉，浓度约50%，收率约35%。
이이을알、병희산갑지위원료，경매극이가성，생성3-갑양기-이을기병희산갑지（산물Ⅰ），재여마람선알화생성3-마람기-이을기병선알（산물Ⅱ），최후경최화렬해득도병희선마람。연구료투료비、반응온도、반응시간등인소대중간산물Ⅱ반응영향。결과표명，최가반응조건위：산물Ⅰ、마람여갑순납마이투료비1：1.2：0.2，반응온도80~90℃，반응시간5~6 h，산물Ⅱ순도가체82%，수솔가체88%。산물Ⅱ재경최화렬해득목표산품병희선마람，농도약50%，수솔약35%。
3-Methoxy-ethyl ProPionate(Ⅰ)was synthesized by Michael addition with diethylamine and methyl acrylate. Therefore,comPoundⅠwas converted to 3-morPholin-diethyl ProPionamide(Ⅱ)by ami-dation with morPholine. Finally,acryloyl morPholinein was obtained by catalytic cracking of intermediatesⅡ. The effect of the ratio of raw material,reaction temPerature and time on intermediates Ⅱwere investi-gated. Result showed that the oPtimum reaction condition were as follows:the Purity of the intermediatesⅡ was uP to 82% and the yield was uP to 88%,when the molar ratio of 3-methoxy-ethyl ProPionate to morPholine and sodium methylate was 1:1 . 2:0 . 2 ,and the best reaction temPerature was 80~90 ℃,the best reaction time was 5~6 h. The Purity of acryloyl morPholine as the target Product was uP to 50% and the yield was uP to 35%.