CAJ | 학술논문

随着近年来对门静脉高压的深入研究，门静脉高压性胆病（PHB）也引起了越来越多的关注。简要的介绍了PHB的病理生理改变、临床表现及主要诊疗方式。PHB的发病机理尚未完全明确，目前推测可能与门静脉海绵状血管瘤的压迫与缺血等因素相关。磁共振胰胆管成像是PHB首选的诊断手段，目前认为无症状的PHB患者无须治疗，症状性的PHB患者的治疗应强调其个体化，治疗的重点应以降低门静脉压力及解除胆道梗阻为主。目前经颈静脉肝内门体分流术等已经成为症状性PHB的一线治疗方法。PHB在临床上并不多见，对于它的了解与认识尚须要更多的实践与研究。
수착근년래대문정맥고압적심입연구，문정맥고압성담병（PHB）야인기료월래월다적관주。간요적개소료PHB적병리생리개변、림상표현급주요진료방식。PHB적발병궤리상미완전명학，목전추측가능여문정맥해면상혈관류적압박여결혈등인소상관。자공진이담관성상시PHB수선적진단수단，목전인위무증상적PHB환자무수치료，증상성적PHB환자적치료응강조기개체화，치료적중점응이강저문정맥압력급해제담도경조위주。목전경경정맥간내문체분류술등이경성위증상성PHB적일선치료방법。PHB재림상상병불다견，대우타적료해여인식상수요경다적실천여연구。
With the progress in research on portal hypertension in recent years,portal hypertensive biliopathy (PHB)has attracted more and more attention.The pathophysiology and clinical manifestations of PHB,as well as the main methods for the diagnosis and treatment of this disease,are briefly described.The pathogenesis of PHB remains unclear,and it has been postulated that the external pressure of portal cav-ernoma and the ischemic stricture of the bile duct may play a role.Magnetic resonance cholangiopancreatography is the primary diagnostic tool for PHB.Currently,it is thought that asymptomatic PHB patients do not require any treatment,and symptomatic PHB patients should re-ceive individualized treatment,which mainly included reducing portal pressure and relieving biliary obstruction.Transjugular intrahepatic portosystemic shunt has become the first-line therapy for symptomatic PHB.More research and practice are needed for further understand-ing of PHB.