临床儿科杂志
臨床兒科雜誌
림상인과잡지
2014年
7期
640-643
,共4页
张凌君%李卫国%盛秋明%戴劲盛%褚陈娟
張凌君%李衛國%盛鞦明%戴勁盛%褚陳娟
장릉군%리위국%성추명%대경성%저진연
窒息%高血糖%低血糖%新生儿
窒息%高血糖%低血糖%新生兒
질식%고혈당%저혈당%신생인
asphyxia%hyperglycemia%hypoglycemia%neonate
目的：探讨足月窒息新生儿血糖监测的临床意义。方法回顾性分析2011年1月至2012年12月收治的足月窒息新生儿在入院24 h内检测的血糖水平及其与预后的关系。结果256例足月窒息新生儿中，血糖异常95例（37.11%），其中低血糖63例（24.61%），高血糖32例（12.50%）；血糖正常161例（62.89%）。低血糖、正常血糖和高血糖三组新生儿，轻度和重度窒息的分布及不同功能损害所累及器官数目的差异有统计学意义（P均<0.001）；三组中足月小样儿、正常出生体质量儿以及巨大儿分布的差异无统计学意义（P=0.094）。256例患儿中，206例轻度窒息，50例重度窒息，重度窒息患儿血糖异常以及高血糖的比例均高于轻度窒息，差异有统计学意义（P均<0.001）；227例（88.67%）累及器官发生功能损害，96例累及1个器官，72例累及2个，59例累及≥3个，三组间血糖异常、低血糖以及高血糖比例差异有统计学意义（P均<0.05）；累及≥3个器官患儿的血糖异常和高血糖比例较高，而累及2个器官患儿低血糖的发生比例较高。结论重度窒息、功能损害所累及器官数多的足月窒息儿更易发生高血糖。
目的：探討足月窒息新生兒血糖鑑測的臨床意義。方法迴顧性分析2011年1月至2012年12月收治的足月窒息新生兒在入院24 h內檢測的血糖水平及其與預後的關繫。結果256例足月窒息新生兒中，血糖異常95例（37.11%），其中低血糖63例（24.61%），高血糖32例（12.50%）；血糖正常161例（62.89%）。低血糖、正常血糖和高血糖三組新生兒，輕度和重度窒息的分佈及不同功能損害所纍及器官數目的差異有統計學意義（P均<0.001）；三組中足月小樣兒、正常齣生體質量兒以及巨大兒分佈的差異無統計學意義（P=0.094）。256例患兒中，206例輕度窒息，50例重度窒息，重度窒息患兒血糖異常以及高血糖的比例均高于輕度窒息，差異有統計學意義（P均<0.001）；227例（88.67%）纍及器官髮生功能損害，96例纍及1箇器官，72例纍及2箇，59例纍及≥3箇，三組間血糖異常、低血糖以及高血糖比例差異有統計學意義（P均<0.05）；纍及≥3箇器官患兒的血糖異常和高血糖比例較高，而纍及2箇器官患兒低血糖的髮生比例較高。結論重度窒息、功能損害所纍及器官數多的足月窒息兒更易髮生高血糖。
목적：탐토족월질식신생인혈당감측적림상의의。방법회고성분석2011년1월지2012년12월수치적족월질식신생인재입원24 h내검측적혈당수평급기여예후적관계。결과256례족월질식신생인중，혈당이상95례（37.11%），기중저혈당63례（24.61%），고혈당32례（12.50%）；혈당정상161례（62.89%）。저혈당、정상혈당화고혈당삼조신생인，경도화중도질식적분포급불동공능손해소루급기관수목적차이유통계학의의（P균<0.001）；삼조중족월소양인、정상출생체질량인이급거대인분포적차이무통계학의의（P=0.094）。256례환인중，206례경도질식，50례중도질식，중도질식환인혈당이상이급고혈당적비례균고우경도질식，차이유통계학의의（P균<0.001）；227례（88.67%）루급기관발생공능손해，96례루급1개기관，72례루급2개，59례루급≥3개，삼조간혈당이상、저혈당이급고혈당비례차이유통계학의의（P균<0.05）；루급≥3개기관환인적혈당이상화고혈당비례교고，이루급2개기관환인저혈당적발생비례교고。결론중도질식、공능손해소루급기관수다적족월질식인경역발생고혈당。
Objective To investigate the clinical significance of monitoring blood glucose in term infants with asphyxia. Methods The blood glucouse within 24 hours of admission and prognosis were retrospectively analyzed in full-term neonates with asphyxia admitted from January, 2011 to December, 2012. Results Among 256 term infants with asphyxia, 95 cases (37.11%) had abnormal blood glucose, 63 cases (24.61%) were hypoglycemia and 32 (12.50%) were hyperglycemia. The incidence of mild asphyxia and severe asphyxia, the number of damaged organ were significantly different among infants with hypoglycemia, normal blood glucose, and hyperglycemia (all P<0.001). Among 256 term infants, 206 cases were mild asphyxia, 50 cases were serve asphyxia. The incidence of abnormal blood glucose and hyperglycemia were significantly higher in infants with serve asphyxia than those in infants with mild asphyxia (P<0.01). Among 256 term infants, 227 cases (88.67%) had organ damaged. 96 cases involved one organ, 72 cases involved two organs, and 59 cases involved three or more organs. The incidence of abnormal blood glucose, hypoglycemia, hyperglucemia were significantly different among infants invoved one, two or threr and more organs. The incidence of hyperglycemia was the highest in infants with three or more organ damaged, and the incidence of hypoglycemia was the highest in infants with two organ damaged. Conclusions The term infants with severe asphyxia and more organ damaged were prone to with abnormal blood glucose.
