CAJ | 학술논문

目的：探讨兰州地区川崎病(KD)患儿并发冠状动脉损害(CAL)的危险因素。方法对确诊的174例KD患儿，根据其是否并发CAL分为CAL组和NCAL组，分析比较其年龄、性别、热程、静脉用丙种球蛋白(IVIG)开始使用时间、IVIG使用剂量、C反应蛋白(CRP)、血清白蛋白、红细胞沉降率(ESR)、血小板(PLT)、血红蛋白等资料的差异。结果174例KD患儿并发CAL者46例(占26.44%)，无并发CAL者128例；两组患儿平均热程、自发热到开始IVIG治疗的时间、IVIG使用剂量，以及PLT、CRP、ESR、红细胞计数(RBC)的差异均有统计学意义(P<0.05)。结论热程>10 d、发热10 d后开始使用IVIG，PLT、CRP、ESR升高，RBC降低的KD患儿应警惕并发CAL的危险性，对于KD的治疗及预后判断有一定的参考价值。
목적：탐토란주지구천기병(KD)환인병발관상동맥손해(CAL)적위험인소。방법대학진적174례KD환인，근거기시부병발CAL분위CAL조화NCAL조，분석비교기년령、성별、열정、정맥용병충구단백(IVIG)개시사용시간、IVIG사용제량、C반응단백(CRP)、혈청백단백、홍세포침강솔(ESR)、혈소판(PLT)、혈홍단백등자료적차이。결과174례KD환인병발CAL자46례(점26.44%)，무병발CAL자128례；량조환인평균열정、자발열도개시IVIG치료적시간、IVIG사용제량，이급PLT、CRP、ESR、홍세포계수(RBC)적차이균유통계학의의(P<0.05)。결론열정>10 d、발열10 d후개시사용IVIG，PLT、CRP、ESR승고，RBC강저적KD환인응경척병발CAL적위험성，대우KD적치료급예후판단유일정적삼고개치。
Objective To investigate the risk factors for coronary artery lesions (CALs) in children with Kawasaki disease (KD) in Lanzhou. Methods One hundred and seventy-four children with diagnosed KD were divided into CAL group and non-CAL group based on the existence of concurrent CALs. The age, gender, fever duration, intravenous immunoglobulin (IVIG) start time, IVIG dose, C-reactive protein (CRP), serum albumin, erythrocyte sedimentation rate (ESR), platelet (PLT), red blood cell count (RBC), hemoglobin and so on were compared. Results Among the 174 children, 46 children (26.44%) were complicated by CALs and 128 children were not. The differences of average fever duration, IVIG starting time, IVIG dose, PLT, CRP, ESR and RBC were statistically signiifcant (P<0.05). Conclusions When KD children has the fever durations>10 d, start of IVIG af-ter 10 days of fever, increase of PLT, CRP and ESR and decrease of RBC, clinicians should be alert to the risk of concurrent CAL.