CAJ | 학술논문

目的：研究中国人群乳腺癌患者发生真空辅助旋切系统活检（VABB）针道种植转移的几率及新辅助化疗对其产生的影响。方法将通过VABB诊断为乳腺癌的病人分为两组，一组直接进行外科开放性手术（直接手术组），一组先进行新辅助化疗后再进行外科开放性手术（新辅助化疗组）。分析两组病人发生针道种植转移的几率，以及两组病人的无病生存（DFS）和总生存（OS），并采用相应的统计学方法进行两组间的比较。结果共有214名患者入组，其中直接手术组94名，新辅助化疗组120名，中位随访时间为29.2月，两组发生针道转移的几率分别为3.2%和0.8%，两者相比无显著性差异（P=0.206，χ2检验）；DFS和OS亦无显著差异（DFS P=0.221，OS P=0.531，Log-rank检验）。结论经VABB后两组乳腺癌患者的针道种植转移率低，新辅助化疗不会导致VABB后的针道种植转移率的增加。
목적：연구중국인군유선암환자발생진공보조선절계통활검（VABB）침도충식전이적궤솔급신보조화료대기산생적영향。방법장통과VABB진단위유선암적병인분위량조，일조직접진행외과개방성수술（직접수술조），일조선진행신보조화료후재진행외과개방성수술（신보조화료조）。분석량조병인발생침도충식전이적궤솔，이급량조병인적무병생존（DFS）화총생존（OS），병채용상응적통계학방법진행량조간적비교。결과공유214명환자입조，기중직접수술조94명，신보조화료조120명，중위수방시간위29.2월，량조발생침도전이적궤솔분별위3.2%화0.8%，량자상비무현저성차이（P=0.206，χ2검험）；DFS화OS역무현저차이（DFS P=0.221，OS P=0.531，Log-rank검험）。결론경VABB후량조유선암환자적침도충식전이솔저，신보조화료불회도치VABB후적침도충식전이솔적증가。
Objective To study the incidence of implantation metastasis of breast cancer in vacuum-assisted breast biopsy (VABB) needle tract in Chinese patients and evaluate the effect of neoadjuvant chemotherapy on needle tract metastasis following VABB. Methods The breast cancer patients with established diagnosis by VABB were divided into two groups to receive open surgery or neoadjuvant chemotherapy prior to open surgery. The incidence of needle tract metastasis, disease-free survival (DFS) and overall survival (OS) were compared between the two groups. Results A total of 214 patients were enrolled, among whom 94 directly underwent surgeries and 120 had neoadjuvant chemotherapy before surgery. The two groups showed no significant differences in the incidence of needle tract metastasis (3.2%vs 0.8%, P=0.206), DFS (P=0.221), or OS (P=0.531). Conclusion The incidence of needle tract metastasis is low after VABB, and neoadjuvant chemotherapy does not increase this risk.