北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
8期
1-1,2
,共2页
双氯芬酸二乙胺凝胶剂%HPLC法%含量测定
雙氯芬痠二乙胺凝膠劑%HPLC法%含量測定
쌍록분산이을알응효제%HPLC법%함량측정
Diclofenac Diethylamine Gel%HPLC%Determination of content
目的：采用HPLC法测定双氯芬酸二乙胺凝胶剂的含量。方法：以甲醇∶4%冰醋酸（70∶30）为流动相，CNW C18色谱柱（150mm×4.6mm，5μm），检测波长为276nm。结果：双氯芬酸钠的测定在51.600～1290.0μg/ml范围内线性关系良好，双氯芬酸钠的平均回收率为101.2%，RSD=1.2%（n=9）。结论：方法简单、灵敏度高，可用于双氯芬酸二乙胺凝胶剂的含量测定。
目的：採用HPLC法測定雙氯芬痠二乙胺凝膠劑的含量。方法：以甲醇∶4%冰醋痠（70∶30）為流動相，CNW C18色譜柱（150mm×4.6mm，5μm），檢測波長為276nm。結果：雙氯芬痠鈉的測定在51.600～1290.0μg/ml範圍內線性關繫良好，雙氯芬痠鈉的平均迴收率為101.2%，RSD=1.2%（n=9）。結論：方法簡單、靈敏度高，可用于雙氯芬痠二乙胺凝膠劑的含量測定。
목적：채용HPLC법측정쌍록분산이을알응효제적함량。방법：이갑순∶4%빙작산（70∶30）위류동상，CNW C18색보주（150mm×4.6mm，5μm），검측파장위276nm。결과：쌍록분산납적측정재51.600～1290.0μg/ml범위내선성관계량호，쌍록분산납적평균회수솔위101.2%，RSD=1.2%（n=9）。결론：방법간단、령민도고，가용우쌍록분산이을알응효제적함량측정。
Objective:The purpose is to develop method for the content determination of Diclofenac Diethylamine Gel. Methods:Separation was performed on a CNW column (150mm×4.6mm,5μm). The mobile phase consists of methanol:4% acetic acid solution (70∶30,v/v). The UV detection was set at 276nm. Results: Diclofenac diethylamine had a good linear relation in the range of 51.600~1290.0μg/ml, the average recovery of Diclofenac diethylamine was 101.1%and the RSD was 1.2%. Conclusion:The method was simple, sensitive and rapid and it could be used for the determination the content in Diclofenac Diethylamine Gel.
