CAJ | 학술논문

原发性高血压是一种全球性多发性疾病，起初是以血压升高为主要表现，继而伴有多个靶器官功能损害和代谢紊乱的全身性疾病。原发性高血压是动脉粥样硬化的独立危险因素，可导致主动脉、颈动脉、脑动脉、冠状动脉、肾动脉、肠系膜动脉及四肢动脉等的粥样硬化，从而引发脑血管意外、冠状动脉粥样硬化性心脏病、慢性肾功能不全等严重疾病。颈动脉较为表浅，病变出现较早，颈动脉内膜-中膜厚度的改变及粥样斑块情况可较好地反映原发性高血压对全身动脉粥样硬化的影响，以及不同血压水平与动脉粥样硬化发生的关系。因此，对原发性高血压患者颈动脉病变的早期识别和准确评价，对疾病的早期防治和疗效评估及预后有重大意义。
원발성고혈압시일충전구성다발성질병，기초시이혈압승고위주요표현，계이반유다개파기관공능손해화대사문란적전신성질병。원발성고혈압시동맥죽양경화적독립위험인소，가도치주동맥、경동맥、뇌동맥、관상동맥、신동맥、장계막동맥급사지동맥등적죽양경화，종이인발뇌혈관의외、관상동맥죽양경화성심장병、만성신공능불전등엄중질병。경동맥교위표천，병변출현교조，경동맥내막-중막후도적개변급죽양반괴정황가교호지반영원발성고혈압대전신동맥죽양경화적영향，이급불동혈압수평여동맥죽양경화발생적관계。인차，대원발성고혈압환자경동맥병변적조기식별화준학평개，대질병적조기방치화료효평고급예후유중대의의。
The primary hypertension (PH) is a global multiple diseases, initially the main performance are blood pressure, then accompanied by multiple target organ damage and metabolic disorders of systemic disease. PH is an independent risk factor for atherosclerosis, which can lead atherosclerosis of aorta, carotid, cerebral artery, coronary, renal artery, superior mesenteric artery and limbs artery, causing cerebral vascular accident, coronary atherosclerotic heart disease, chronic renal failure and other serious diseases. Carotid artery is relatively superficial, the lesions appear earlier, and the examinations are noninvasive, convenient and accurate. The change of carotid intima-media thickness and atheromatous plaque, may well reflect the influence of PH on systemic atherosclerosis, as well as the relationship between different blood pressure and atherosclerosis. Therefore, early recognition and accurate assessment on carotid artery disease of patients with PH, would have great significance on early prevention, efficacy evaluation and prognosis of the disease.