CAJ | 학술논문

目的：探讨肺头比（CVR）在胎儿隔离肺预后评估中的价值。方法分析广东省妇幼保健院2010年5月至2013年6月产前超声诊断为隔离肺胎儿共75例，测量胎儿CVR，追踪其临床预后。结果75例隔离肺胎儿中，62例CVR＜1.6，孕期均无出现水肿，出生后均存活且无呼吸系统症状；13例CVR≥1.6，其中7例（53.8%，7/13）合并胎儿水肿，11例存活，9例（69.2%，9/13）出生后出现呼吸系统症状，2例引产。两组胎儿水肿发生率及出生后呼吸系统症状发生率χ2分别为30.372及36.13，差异均具有统计学意义（P＜0.01）。48例出生后行手术治疗，所有手术病例全部治愈，病理检查42例为单纯隔离肺，6例为隔离肺合并肺囊腺瘤。结论不合并胎儿水肿的隔离肺预后良好，CVR 是产前评估胎儿隔离肺预后的有效指标，CVR≥1.6与胎儿水肿及出生后出现症状相关。
목적：탐토폐두비（CVR）재태인격리폐예후평고중적개치。방법분석광동성부유보건원2010년5월지2013년6월산전초성진단위격리폐태인공75례，측량태인CVR，추종기림상예후。결과75례격리폐태인중，62례CVR＜1.6，잉기균무출현수종，출생후균존활차무호흡계통증상；13례CVR≥1.6，기중7례（53.8%，7/13）합병태인수종，11례존활，9례（69.2%，9/13）출생후출현호흡계통증상，2례인산。량조태인수종발생솔급출생후호흡계통증상발생솔χ2분별위30.372급36.13，차이균구유통계학의의（P＜0.01）。48례출생후행수술치료，소유수술병례전부치유，병리검사42례위단순격리폐，6례위격리폐합병폐낭선류。결론불합병태인수종적격리폐예후량호，CVR 시산전평고태인격리폐예후적유효지표，CVR≥1.6여태인수종급출생후출현증상상관。
Objective To investigate the value of congenital cystic adenomatoid malformation (CCAM) volume ratio (CVR) in pulmonary sequestrations (PS) prognostic of the fetus.Methods75 cases of fetal PS diagnosed by prenatal ultrasound in Guangdong Women and Children Hospital from May 2010 to June 2013 were measured of the fetal CVR, their clinical outcomes were observed.ResultsIn 75 cases of fetal PS, 62 cases of CVR<1.6 survived with no edema during pregnancy and without respiratory symptoms after birth; Among the 13 cases of CVR≥1.6, 7 patients (53.8%, 7/13) combined with fetal hydrops, 11 patients survived, 9 cases (69.2%, 9/13) with respiratory symptoms after birth, 2 cases of abortion.The incidence of fetal hydrops groups and incidence of respiratory symptoms after birth(χ2=30.372 and 36.13,P value<0.01) were statistically different.48 cases received surgery after birth and all surgical cases were cured. Pathological examination indicated 42 cases were pathological PS alone while 6 cases of PS co-existing with CCAM.ConclusionPS specific absence of hydrop was a congenital disorder with an excellent prognosis. CVR was a valid indicator of PS prenatal assessment, CVR≥1.6 was associated with fetal hydrops and postnatal symptoms.