中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
13期
2389-2393
,共5页
刘鹏%欧阳泽伟%蒲晓群%贺琳%石向江%欧阳小燕
劉鵬%歐暘澤偉%蒲曉群%賀琳%石嚮江%歐暘小燕
류붕%구양택위%포효군%하림%석향강%구양소연
心绞痛,不稳定型%脂肪酸类,非酯化%血管成形术,经腔,经皮冠状动脉%血运重建
心絞痛,不穩定型%脂肪痠類,非酯化%血管成形術,經腔,經皮冠狀動脈%血運重建
심교통,불은정형%지방산류,비지화%혈관성형술,경강,경피관상동맥%혈운중건
Angina,unstable%Fatty acids,nonesterified%Angioplasty,transluminal,percutaneous coronary%Coronary revascularization
目的：观察血清游离脂肪酸（FFA）在部分和完全血运重建的冠状动脉介入术（PCI）治疗不稳定型心绞痛（UA）患者中的浓度变化，评价其与冠状动脉血运重建之间的关系。方法入选65例UA患者，于PCI术前及术后当时、术后1周抽血查血清FFA水平，并根据是否完全血运重建分为部分血运重建组33例，完全血运重建组32例，并选取30例经冠状动脉造影未见冠状动脉病变患者作为对照组。应用加拿大心血管病学会（CCS）劳累性心绞痛分级标准及6 min步行试验评价各组患者术前、术后心绞痛及心功能情况并进行比较。结果术前及术后当时PCI组血清 FFA 水平高于对照组（P＜0.05），但部分血运重建组与完全血运重建组差异无统计学意义（P＞0.05）；术后1周完全血运重建组FFA与对照组接近，差异无统计学意义（P＞0.05），但显著低于不完全血运重建组（P＜0.05）。结论血清FFA含量可能是判断冠状动脉介入治疗预后的一个指标。
目的：觀察血清遊離脂肪痠（FFA）在部分和完全血運重建的冠狀動脈介入術（PCI）治療不穩定型心絞痛（UA）患者中的濃度變化，評價其與冠狀動脈血運重建之間的關繫。方法入選65例UA患者，于PCI術前及術後噹時、術後1週抽血查血清FFA水平，併根據是否完全血運重建分為部分血運重建組33例，完全血運重建組32例，併選取30例經冠狀動脈造影未見冠狀動脈病變患者作為對照組。應用加拿大心血管病學會（CCS）勞纍性心絞痛分級標準及6 min步行試驗評價各組患者術前、術後心絞痛及心功能情況併進行比較。結果術前及術後噹時PCI組血清 FFA 水平高于對照組（P＜0.05），但部分血運重建組與完全血運重建組差異無統計學意義（P＞0.05）；術後1週完全血運重建組FFA與對照組接近，差異無統計學意義（P＞0.05），但顯著低于不完全血運重建組（P＜0.05）。結論血清FFA含量可能是判斷冠狀動脈介入治療預後的一箇指標。
목적：관찰혈청유리지방산（FFA）재부분화완전혈운중건적관상동맥개입술（PCI）치료불은정형심교통（UA）환자중적농도변화，평개기여관상동맥혈운중건지간적관계。방법입선65례UA환자，우PCI술전급술후당시、술후1주추혈사혈청FFA수평，병근거시부완전혈운중건분위부분혈운중건조33례，완전혈운중건조32례，병선취30례경관상동맥조영미견관상동맥병변환자작위대조조。응용가나대심혈관병학회（CCS）로루성심교통분급표준급6 min보행시험평개각조환자술전、술후심교통급심공능정황병진행비교。결과술전급술후당시PCI조혈청 FFA 수평고우대조조（P＜0.05），단부분혈운중건조여완전혈운중건조차이무통계학의의（P＞0.05）；술후1주완전혈운중건조FFA여대조조접근，차이무통계학의의（P＞0.05），단현저저우불완전혈운중건조（P＜0.05）。결론혈청FFA함량가능시판단관상동맥개입치료예후적일개지표。
Objective To observe the changes of serum levels of free fatty acid in patients with unstable angina treated with complete or incomplete revascularization after percutaneous coronary intervention and to investigate its clinical value and to investigate the relationship between their concentration variances and coronary revascularization.Methods 65 patients with unstable angina were enrolled in this study and 30 persons without coronary heart diseases were selected as the control. According to revascularization form, the unstable angina group was divided into complete revascularization group (32 cases) and incomplete revascularization group (33 cases). All cases were respectively measured serum FFA levels before and after PCI and one week after PCI. The 6 minute walk test and angina classification according to CCS were used to evaluate the improvement of exercise capacity after PCI.Results The serum levels of FFA in unstable angina before and after PCI were obviously higher than those in control group (P<0.05). The serum levels of FFA in complete revascularization group one week after PCI were significant lower than those in incomplete revascularization group (P<0.05). Conclusion FFA may be helpful to judge prognosis of unstable angina after PCI.
