CAJ | 학술논문

目的：探讨脾肾阳虚型慢性心力衰竭(chronic heart failure,CHF)患者与非脾肾阳虚型慢性心力衰竭患者血浆中氨基末端B型利钠肽前体(NT-proBNP)和同型半胱氨酸(HCY)的水平及临床意义。方法将慢性心力衰竭患者进行中医辨证分型,选取脾肾阳虚型患者(A组)与非脾肾阳虚型患者(B组),各60例。检测两组患者血浆NT-proBNP、HCY水平,并对两组数值进行比较。结果 A组患者NT-proBNP和HCY水平明显高于B组,差异有高度统计学意义(P<0.01)。随着心力衰竭分级增加,患者NT-proBNP、HCY水平也逐渐增加,差异有高度统计学意义(P<0.01)。结论 NT-proBNP、HCY可以作为评价脾肾阳虚型心力衰竭患者心衰严重程度的客观性指标,并具有临床可操作性。
목적：탐토비신양허형만성심력쇠갈(chronic heart failure,CHF)환자여비비신양허형만성심력쇠갈환자혈장중안기말단B형리납태전체(NT-proBNP)화동형반광안산(HCY)적수평급림상의의。방법장만성심력쇠갈환자진행중의변증분형,선취비신양허형환자(A조)여비비신양허형환자(B조),각60례。검측량조환자혈장NT-proBNP、HCY수평,병대량조수치진행비교。결과 A조환자NT-proBNP화HCY수평명현고우B조,차이유고도통계학의의(P<0.01)。수착심력쇠갈분급증가,환자NT-proBNP、HCY수평야축점증가,차이유고도통계학의의(P<0.01)。결론 NT-proBNP、HCY가이작위평개비신양허형심력쇠갈환자심쇠엄중정도적객관성지표,병구유림상가조작성。
Objective To investigate the clinical significance of plasma NT-proBNP and HCY in chronic heart failure patients with spleen kidney yang deficiency type and non-spleen and kidney yang deficiency type. Methods The pa-tients with chronic heart failure were divided into spleen kidney yang deficiency type (group A) and non-spleen and kidney yang deficiency type (group B) by syndrome differentiation of traditional Chinese medicine, and each group had 60 patients. The levels of plasma NT-proBNP, HCY in the two groups were tested and compared. Results The levels of plasma NT-proBNP, HCY in group A were significantly higher than those in group B, the differences were statistically significant (P < 0.01). With the increase of cardiac functional grading, the levels of plasma NT-proBNP, HCY in-creased, the differences were statistically significant (P<0.01). Conclusion NT-proBNP, HCY can be used as objectiv-ity index for seriousness evaluation in chronic heart failure patients with spleen kidney yang deficiency type, and have clinical feasibility.