中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
20期
13-14
,共2页
缬沙坦%氢氯噻嗪%高血压心脏病%治疗效果
纈沙坦%氫氯噻嗪%高血壓心髒病%治療效果
힐사탄%경록새진%고혈압심장병%치료효과
Valsartan%Hydrochlorothiazide%Hypertensive heart disease%Clinical effect
目的：探讨缬沙坦与氢氯噻嗪联合治疗高血压心脏病的效果。方法：2013年1月-2014年1月收治高血压心脏病患者120例，将其平均分为对照组和观察组。对照组采用缬沙坦治疗，观察组采用缬沙坦与氢氯噻嗪联合治疗，对两组临床治疗效果、收缩压、舒张压、超声心电图指标、不良反应等进行分析比较。结果：观察组治疗总有效率96.67%，对照组治疗总有效率71.67%，两组比较差异具有统计学意义(P＜0.05)。观察组舒张压、收缩压下降程度明显，对照组治疗后舒张压、收缩压下降也相对明显，与治疗前相比，两组血压下降程度明显，P＜0.05，具有统计学意义。治疗后观察组和对照组的血压下降程度比较，观察组更为明显，P＜0.05，差异具有统计学意义。两组治疗后超声心电图各项指标的降低幅度与治疗前相比，差异具有统计学意义(P＜0.05)。观察组不良反应发生率6.67%，对照组10.00%，P＞0.0.5，差异无统计学意义。结论：缬沙坦与氢氯噻嗪联合治疗高血压心脏病，效果非常显著，可改善患者的心脏功能，在高血压心脏病临床治疗中有重要的价值。
目的：探討纈沙坦與氫氯噻嗪聯閤治療高血壓心髒病的效果。方法：2013年1月-2014年1月收治高血壓心髒病患者120例，將其平均分為對照組和觀察組。對照組採用纈沙坦治療，觀察組採用纈沙坦與氫氯噻嗪聯閤治療，對兩組臨床治療效果、收縮壓、舒張壓、超聲心電圖指標、不良反應等進行分析比較。結果：觀察組治療總有效率96.67%，對照組治療總有效率71.67%，兩組比較差異具有統計學意義(P＜0.05)。觀察組舒張壓、收縮壓下降程度明顯，對照組治療後舒張壓、收縮壓下降也相對明顯，與治療前相比，兩組血壓下降程度明顯，P＜0.05，具有統計學意義。治療後觀察組和對照組的血壓下降程度比較，觀察組更為明顯，P＜0.05，差異具有統計學意義。兩組治療後超聲心電圖各項指標的降低幅度與治療前相比，差異具有統計學意義(P＜0.05)。觀察組不良反應髮生率6.67%，對照組10.00%，P＞0.0.5，差異無統計學意義。結論：纈沙坦與氫氯噻嗪聯閤治療高血壓心髒病，效果非常顯著，可改善患者的心髒功能，在高血壓心髒病臨床治療中有重要的價值。
목적：탐토힐사탄여경록새진연합치료고혈압심장병적효과。방법：2013년1월-2014년1월수치고혈압심장병환자120례，장기평균분위대조조화관찰조。대조조채용힐사탄치료，관찰조채용힐사탄여경록새진연합치료，대량조림상치료효과、수축압、서장압、초성심전도지표、불량반응등진행분석비교。결과：관찰조치료총유효솔96.67%，대조조치료총유효솔71.67%，량조비교차이구유통계학의의(P＜0.05)。관찰조서장압、수축압하강정도명현，대조조치료후서장압、수축압하강야상대명현，여치료전상비，량조혈압하강정도명현，P＜0.05，구유통계학의의。치료후관찰조화대조조적혈압하강정도비교，관찰조경위명현，P＜0.05，차이구유통계학의의。량조치료후초성심전도각항지표적강저폭도여치료전상비，차이구유통계학의의(P＜0.05)。관찰조불량반응발생솔6.67%，대조조10.00%，P＞0.0.5，차이무통계학의의。결론：힐사탄여경록새진연합치료고혈압심장병，효과비상현저，가개선환자적심장공능，재고혈압심장병림상치료중유중요적개치。
Objective:To investigate the effects of valsartan combined with hydrochlorothiazide in the treatment of hypertensive heart disease.Methods:120 cases with hypertensive heart disease were selected from January 2013 to January 2014.They were randomly divided into the control group and the observation group.The control group were treated with valsartan.The observation group were treated with valsartan combined with hydrochlorothiazide.Then compare clinical therapeutic effect,systolic blood pressure,diastolic blood pressure,ultrasonic electrocardiogram and adverse reaction in two groups.Results:The total efficiency in the observation group was 96.67%,and in the control group was 71.67%.The difference was statistically significant,P<0.05.When compared with pretherapy,diastolic blood pressure and systolic blood pressure of two groups both decreased significantly after treatment,and the difference were statistically significant,P<0.05.The observation group decreased more obviously than the control group,and the difference were statistically significant,P<0.05.When compared with pretherapy,ultrasound ECG indexes of two groups both decreased significantly after treatment,and the difference were statistically significant,P<0.05.The rate of adverse reaction of the observation groups was 6.67%,and that of the control group was 10%.There was no statistical significance, P>0.05,.Conclusion:Valsartan combined with hydrochlorothiazide in the treatment of hypertensive heart disease achieved an significant effect,It can improved the cardiac function of patients.So it has important value in clinical treatment of hypertensive heart disease.
