CAJ | 학술논문

目的探讨干预前后我院围手术期预防用抗菌药物的合理性和干预措施的效果。方法分别调取我院2012年1~8月出院病例1029例纳入干预前组，2013年1~8月出院病例950例纳入干预后组，对两组的预防用药情况进行分析。结果行政干预+临床药师干预后，我院I类切口抗菌药物预防使用率从64.1%降至36.6%；预防用药时间≤24h率由36.3%升至76.7%。I、II类手术切口术前0.5~2h给药合理率由89.2%升至95.4%；品种选择合理率由26.6%上升至88.9%。结论行政部门和临床药师的共同干预下，可有效引导围手术期预防用药。
목적탐토간예전후아원위수술기예방용항균약물적합이성화간예조시적효과。방법분별조취아원2012년1~8월출원병례1029례납입간예전조，2013년1~8월출원병례950례납입간예후조，대량조적예방용약정황진행분석。결과행정간예+림상약사간예후，아원I류절구항균약물예방사용솔종64.1%강지36.6%；예방용약시간≤24h솔유36.3%승지76.7%。I、II류수술절구술전0.5~2h급약합리솔유89.2%승지95.4%；품충선택합리솔유26.6%상승지88.9%。결론행정부문화림상약사적공동간예하，가유효인도위수술기예방용약。
Objective To explore the rationality of preventive antibiotic use during perioperative period and investigate the ef ect of the intervention measures.Methods 1029 discharged patients from Januaryto August of 2012 were included in non-intervention group and 950 discharged patients from January to August of 2013were included in intervention group, the rationality of prophylactic application of antibiotics in clean surgery was copared between the two groups.Results After administrative intervention+clinical pharmacist intervention,the antibiotics utilization rate decreased from 64.1%to 36.6%;the rational ratio of course of antibiotic treatment increase from 36.3%to 76.7%;the rational ratio of administering opportunity before the operation increase from 89.2% to 95.4%;the rational ratio of antibiotic selection increased from 26.6%to 88.9%.Conclusion Administrative intervention+clinical pharmacists can effectively improve the levelof prophylactic use of antibiotics during perioperative period.