中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
20期
22-23
,共2页
DNA倍体分析%癌胚抗原%胸腔积液%诊断价值
DNA倍體分析%癌胚抗原%胸腔積液%診斷價值
DNA배체분석%암배항원%흉강적액%진단개치
DNA ploidy analysis%CEA%Pleural effusion%Diagnostic value
目的：对胸腔积液患者的胸水脱落细胞进行DNA倍体分析和癌胚抗原检测，将两种方法进行比较，评估其诊断价值。方法选取经过临床确诊的56例胸腔积液患者作为观察组，56例良性胸腔积液患者作为对照组，对胸水脱落细胞进行DNA倍体分析和癌胚抗原检测。结果 DNA倍体分析的特异度为80.36%，灵敏度为83.93%，Youden指数为0.7029；CEA检测的特异度为96.43%，灵敏度为60.71%，Youden指数为0.5714，两种诊断方法在灵敏度和特异度方面差异有统计学意义(P<0.05，P<0.01)，而在Youden指数方面差异无统计学意义(P>0.05)。结论 DNA倍体分析检测胸腔积液的灵敏度和特异度更高，如果和CEA联用，诊断价值更高。
目的：對胸腔積液患者的胸水脫落細胞進行DNA倍體分析和癌胚抗原檢測，將兩種方法進行比較，評估其診斷價值。方法選取經過臨床確診的56例胸腔積液患者作為觀察組，56例良性胸腔積液患者作為對照組，對胸水脫落細胞進行DNA倍體分析和癌胚抗原檢測。結果 DNA倍體分析的特異度為80.36%，靈敏度為83.93%，Youden指數為0.7029；CEA檢測的特異度為96.43%，靈敏度為60.71%，Youden指數為0.5714，兩種診斷方法在靈敏度和特異度方麵差異有統計學意義(P<0.05，P<0.01)，而在Youden指數方麵差異無統計學意義(P>0.05)。結論 DNA倍體分析檢測胸腔積液的靈敏度和特異度更高，如果和CEA聯用，診斷價值更高。
목적：대흉강적액환자적흉수탈락세포진행DNA배체분석화암배항원검측，장량충방법진행비교，평고기진단개치。방법선취경과림상학진적56례흉강적액환자작위관찰조，56례량성흉강적액환자작위대조조，대흉수탈락세포진행DNA배체분석화암배항원검측。결과 DNA배체분석적특이도위80.36%，령민도위83.93%，Youden지수위0.7029；CEA검측적특이도위96.43%，령민도위60.71%，Youden지수위0.5714，량충진단방법재령민도화특이도방면차이유통계학의의(P<0.05，P<0.01)，이재Youden지수방면차이무통계학의의(P>0.05)。결론 DNA배체분석검측흉강적액적령민도화특이도경고，여과화CEA련용，진단개치경고。
Objective To assess the value of DNA ploidy analysis and carcinoembryonic antigen in the diagnosis of pleural effu-sion by comparing the two methods applied in the detection of hydrothorax exfoliative cells of the patients with pleural effusion. Methods 56 patients diagnosed with pleural effusion clinically were selected as the observation group, and other 56 patients with benign pleural effusion were selected as the control group. The hydrothorax exfoliative cells of the patients were detected by DNA ploidy analysis and CEA. Results The specificity of the DNA ploidy analysis was 80.36%, the sensitivity was 83.93%, Youden in-dex was 0.7029; The specificity of the CEA detection was 96.43%, the sensitivity was 60.71%, the Youden's index was 0.5714. There was significant difference in sensitivity between the two detection methods (P<0.05) as well as in specificity (P<0.01), but not in the Youden's index (P>0.05). Conclusion The sensitivity and specificity of DNA ploidy analysis are higher, and its diagno-sis value will be higher if it is combined with CEA detection.
