中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
21期
70-71
,共2页
早期综合治疗%新生儿%缺氧缺血性脑病
早期綜閤治療%新生兒%缺氧缺血性腦病
조기종합치료%신생인%결양결혈성뇌병
Early%Comprehensive treatment%Neonatal hypoxic ischemic encephalopathy
目的：探讨新生儿缺氧缺血性脑病早期综合治疗的临床疗效。方法：2011年2月-2013年6月收治新生儿缺氧缺血性脑病患儿66例，随机分成综合治疗组和对照组各33例，对照组采用传统三支持和三对症方法治疗。综合治疗组在对照组的基础上进行综合治疗。结果：经过治疗，综合治疗组显效22例，有效9例，无效2例，总有效率93.9%；对照组显效15例，有效9例，无效6例，死亡3例，总有效率72.7%，两组比较差异有统计学意义(P＜0.05)。综合治疗组在治疗6个月、12个月运动和智力评分明显高于对照组，两组比较差异有统计学意义(P＜0.05)。综合治疗组出现后遗症3例，后遗症发生率9.1%，其中发生脑瘫1例，智力低下1例，听觉障碍1例；对照组出现后遗症8例，后遗症发生率24.2%，其中发生癫痫1例，脑瘫2例，智力低下3例，听觉障碍1例，视觉障碍1例。结论：早期综合疗法治疗早期新生儿缺氧缺血性脑病疗效显著，值得推广。
目的：探討新生兒缺氧缺血性腦病早期綜閤治療的臨床療效。方法：2011年2月-2013年6月收治新生兒缺氧缺血性腦病患兒66例，隨機分成綜閤治療組和對照組各33例，對照組採用傳統三支持和三對癥方法治療。綜閤治療組在對照組的基礎上進行綜閤治療。結果：經過治療，綜閤治療組顯效22例，有效9例，無效2例，總有效率93.9%；對照組顯效15例，有效9例，無效6例，死亡3例，總有效率72.7%，兩組比較差異有統計學意義(P＜0.05)。綜閤治療組在治療6箇月、12箇月運動和智力評分明顯高于對照組，兩組比較差異有統計學意義(P＜0.05)。綜閤治療組齣現後遺癥3例，後遺癥髮生率9.1%，其中髮生腦癱1例，智力低下1例，聽覺障礙1例；對照組齣現後遺癥8例，後遺癥髮生率24.2%，其中髮生癲癇1例，腦癱2例，智力低下3例，聽覺障礙1例，視覺障礙1例。結論：早期綜閤療法治療早期新生兒缺氧缺血性腦病療效顯著，值得推廣。
목적：탐토신생인결양결혈성뇌병조기종합치료적림상료효。방법：2011년2월-2013년6월수치신생인결양결혈성뇌병환인66례，수궤분성종합치료조화대조조각33례，대조조채용전통삼지지화삼대증방법치료。종합치료조재대조조적기출상진행종합치료。결과：경과치료，종합치료조현효22례，유효9례，무효2례，총유효솔93.9%；대조조현효15례，유효9례，무효6례，사망3례，총유효솔72.7%，량조비교차이유통계학의의(P＜0.05)。종합치료조재치료6개월、12개월운동화지력평분명현고우대조조，량조비교차이유통계학의의(P＜0.05)。종합치료조출현후유증3례，후유증발생솔9.1%，기중발생뇌탄1례，지력저하1례，은각장애1례；대조조출현후유증8례，후유증발생솔24.2%，기중발생전간1례，뇌탄2례，지력저하3례，은각장애1례，시각장애1례。결론：조기종합요법치료조기신생인결양결혈성뇌병료효현저，치득추엄。
Objective:To investigate the clinical effect of early comprehensive treatment on neonatal hypoxic ischemic encephalopathy.Methods:66 cases of neonatal hypoxic ischemic encephalopathy were selected from February 2011 to June 2013. They were randomly divided into the treatment group and the control group with 33 cases in each.The control group were given the traditional treatment of three support and three symptomatic.The treatment group were given comprehensive treatment on the basis of the traditional treatment.Results:After treatment,in the treatment group 22 cases of excellence,9 cases of effective,2 cases of invalid,the total efficiency was 93.9%.In the control group 15 cases of excellence,9 cases of effective,6 cases of ineffective,3 cases died,and the total efficiency was 72.7% .The difference was statistically significant between the two groups(P<0.05). Exercise and intelligence score of 6 months and 12 months after treatment in the treatment group was significantly higher than that in the control group.The difference was statistically significant(P<0.05).In the treatment group 3 cases of sequelae,the occurrence rate of sequelae was 9.1%,including 1 cases of cerebral palsy,1 cases of low intelligence,1 cases of hearing impairment. In the control group 8 cases of sequelae,the occurrence rate of sequelae was 24.2%,1 cases of epilepsy,2 cases of cerebral palsy,3 cases of low intelligence,1 cases of hearing impairment,1 cases of visual impairment.Conclusion:Early comprehensive therapy in early neonatal hypoxic ischemic encephalopathy is effective.It is worthy of promotion.
