CAJ | 학술논문

目的：探讨间隔补铁治疗小儿缺铁性贫血的临床意义。方法：将46例缺铁性贫血的小儿随机分为两组，各23例。组1每周2天给药(间隔3天)，组2每天给药，经12周补铁治疗，以血红蛋白(Hb)、血清铁蛋白(SF)作为评价治疗效果的血液学指标，并观察不同补铁方式的不良反应发生情况。结果：两组在治疗后Hb、SF值均有不同程度的上升，与治疗前相比，差异有统计学意义(P＜0.01)；治疗后两组 Hb、SF 值差异无统计学意义(P＞0.05)；每周2天给药组不良反应明显减少。结论：间隔补铁在纠正贫血上与每日补铁同样有效且不良反应少。
목적：탐토간격보철치료소인결철성빈혈적림상의의。방법：장46례결철성빈혈적소인수궤분위량조，각23례。조1매주2천급약(간격3천)，조2매천급약，경12주보철치료，이혈홍단백(Hb)、혈청철단백(SF)작위평개치료효과적혈액학지표，병관찰불동보철방식적불량반응발생정황。결과：량조재치료후Hb、SF치균유불동정도적상승，여치료전상비，차이유통계학의의(P＜0.01)；치료후량조 Hb、SF 치차이무통계학의의(P＞0.05)；매주2천급약조불량반응명현감소。결론：간격보철재규정빈혈상여매일보철동양유효차불량반응소。
Objective:To investigate the clinical significance of intermittent iron treatment on children with iron deficiency anemia.Methods:46 children with iron deficiency anemia were randomly divided into two groups with 23 cases in each.In group 1 drug administration for two times every week (3 days apart).In group 2 drug administration for every day.After12 weeks of iron therapy, using hemoglobin (Hb) and serum ferritin (SF) as blood index to evaluate the therapeutic effect.Then observe the occurrence of adverse reactions in different iron supplements.Results:After treatment,Hb and SF in two groups both increased in varying degrees when compared before the treatment,and the difference were statistically significant(P<0.01).The value of Hb and SF in two groups had no difference after treatment(P>0.05).Drug administration for two times every week in group 1 can reduce side effect significantly.Conclusion:In the correction of anemia,intermittent iron and daily iron supplement had equally effect and less side effects.