CAJ | 학술논문

目的：通过检测脑卒中后偏瘫患者的骨密度（ BMD ）及血清瘦素（ LP ）、碱性磷酸酶（ ALP ）、骨钙素（BGP）、白介素-6（IL-6）水平，观察神经肌肉促进技术（NFT）对其肢体骨质疏松的影响。方法将52例脑卒中偏瘫患者随机分为治疗组和对照组，对照组行常规治疗，治疗组在常规治疗基础上早期给予NFT治疗。采用双能X线吸收法检测两组入院第2天及治疗6个月后的BMD，采用ELISA法检测两组血清LP、ALP、BGP、IL-6水平，并进行比较。结果6个月后两组患肢BMD、对照组健肢与患肢BMD比较差异均有统计学意义（P均＜0．05）；两组血清LP、ALP、BGP、IL-6水平比较差异均有统计学意义（P＜0．05或＜0．01）。结论 NFT能影响脑卒中后偏瘫患者骨代谢指标，增加偏瘫肢体BMD；NFT对防治脑卒中后偏瘫患者的骨质疏松有效。
목적：통과검측뇌졸중후편탄환자적골밀도（ BMD ）급혈청수소（ LP ）、감성린산매（ ALP ）、골개소（BGP）、백개소-6（IL-6）수평，관찰신경기육촉진기술（NFT）대기지체골질소송적영향。방법장52례뇌졸중편탄환자수궤분위치료조화대조조，대조조행상규치료，치료조재상규치료기출상조기급여NFT치료。채용쌍능X선흡수법검측량조입원제2천급치료6개월후적BMD，채용ELISA법검측량조혈청LP、ALP、BGP、IL-6수평，병진행비교。결과6개월후량조환지BMD、대조조건지여환지BMD비교차이균유통계학의의（P균＜0．05）；량조혈청LP、ALP、BGP、IL-6수평비교차이균유통계학의의（P＜0．05혹＜0．01）。결론 NFT능영향뇌졸중후편탄환자골대사지표，증가편탄지체BMD；NFT대방치뇌졸중후편탄환자적골질소송유효。
Objective To observe the therapeutic effect of neuromuscular facilitation techniques (NFT) on hemiplegic stroke patients'osteoporosis through the detections of serum leptin (LP), alkaline phosphatase (ALP), bone gla-protein (BGP), interleukin-6 (IL-6) and bone mineral density (BMD).Methods Fifty-two hemiplegic stroke patients were randomly divided into 2 groups:the control group which received conventional treatment, and the treatment group which received NFT early be-sides conventional treatment.The serum LP, ALP, BGP, IL-6 and BMD of all cases in the second day of admission and 6 months after the treatment were detected by using ELISA method and double X-ray absorption method, and then contrastive analysis was conducted.Results The BMD of hemiplegic limbs between the two groups 6 months later, and the BMD between the hemiplegic limbs and the healthy limbs in the control group 6 months later all had statistically significant differences (all P<0.05).The se-rum ALP, BGP, IL-6 and LP levels 6 months later all had statistically significant differences between the two groups ( all P<0.05 or P<0.01).Conclusions NFT can affect the patients'bone metabolic markers and increase the BMD of hemiplegic limbs;NFT should be given to the hemiplegic stroke patients for the prevention and treatment of osteoporosis .