中国卫生产业
中國衛生產業
중국위생산업
CHINA HEALTH INDUSTRY
2014年
21期
25-26
,共2页
糖尿病周围神经病变%硫辛酸%甲钴胺
糖尿病週圍神經病變%硫辛痠%甲鈷胺
당뇨병주위신경병변%류신산%갑고알
Diabetic peripheral neuropathy%Lipoic acid%Mecobalamin
目的：分析硫辛酸治疗糖尿病周围神经病变的疗效，探讨其临床适用性。方法选取从2013年1月1日-2014年4月30日于我院接受治疗的43例糖尿病周围神经病变患者作为病例资料，随机分为研究组和对照组两组，对照组采用甲钴胺进行治疗，研究组硫辛酸进行治疗。观察并记录两组患者治疗前后正中神经、胫神经、尺神经的传导速度以及两组患者治疗后的总有效率，并且进行比较。结果治疗后研究组患者正中神经传速为(47.57±4.26) m/s、尺神经为（44.56±2.83）m/s、胫神经为（45.37±3.43）m/s，而对照组正中神经为(43.45±3.18) m/s、尺神经为（40.21±2.16）m/s、胫神经为（41.23±3.19）m/s，两组对比，研究组患者的正中神经、尺神经、胫神经传导速度均明显优于对照组，差异有统计学意义（P<0.05）；治疗后研究组患者总有效率为83.9%，对照组患者总有效率为41.7%，两组对比，差异具有统计学意义（χ2=7.6592，P=0.0056）。结论硫辛酸治疗糖尿病周围神经病变的效果良好，适合临床长期推广应用。
目的：分析硫辛痠治療糖尿病週圍神經病變的療效，探討其臨床適用性。方法選取從2013年1月1日-2014年4月30日于我院接受治療的43例糖尿病週圍神經病變患者作為病例資料，隨機分為研究組和對照組兩組，對照組採用甲鈷胺進行治療，研究組硫辛痠進行治療。觀察併記錄兩組患者治療前後正中神經、脛神經、呎神經的傳導速度以及兩組患者治療後的總有效率，併且進行比較。結果治療後研究組患者正中神經傳速為(47.57±4.26) m/s、呎神經為（44.56±2.83）m/s、脛神經為（45.37±3.43）m/s，而對照組正中神經為(43.45±3.18) m/s、呎神經為（40.21±2.16）m/s、脛神經為（41.23±3.19）m/s，兩組對比，研究組患者的正中神經、呎神經、脛神經傳導速度均明顯優于對照組，差異有統計學意義（P<0.05）；治療後研究組患者總有效率為83.9%，對照組患者總有效率為41.7%，兩組對比，差異具有統計學意義（χ2=7.6592，P=0.0056）。結論硫辛痠治療糖尿病週圍神經病變的效果良好，適閤臨床長期推廣應用。
목적：분석류신산치료당뇨병주위신경병변적료효，탐토기림상괄용성。방법선취종2013년1월1일-2014년4월30일우아원접수치료적43례당뇨병주위신경병변환자작위병례자료，수궤분위연구조화대조조량조，대조조채용갑고알진행치료，연구조류신산진행치료。관찰병기록량조환자치료전후정중신경、경신경、척신경적전도속도이급량조환자치료후적총유효솔，병차진행비교。결과치료후연구조환자정중신경전속위(47.57±4.26) m/s、척신경위（44.56±2.83）m/s、경신경위（45.37±3.43）m/s，이대조조정중신경위(43.45±3.18) m/s、척신경위（40.21±2.16）m/s、경신경위（41.23±3.19）m/s，량조대비，연구조환자적정중신경、척신경、경신경전도속도균명현우우대조조，차이유통계학의의（P<0.05）；치료후연구조환자총유효솔위83.9%，대조조환자총유효솔위41.7%，량조대비，차이구유통계학의의（χ2=7.6592，P=0.0056）。결론류신산치료당뇨병주위신경병변적효과량호，괄합림상장기추엄응용。
Objective To analyze the effects of lipoic acid on diabetic peripheral neuropathy, and discuss its clinical applicability. Methods 43 cases of diabetic peripheral neuropathy patients from January 1, 2013 to April 30, 2014 in our hospital were treated as clinical data ,and were randomly divided into the study group and the control group , the control group were treated with mecobalamin the study group were treated with lipoic acid. Observed and recorded around treatment the median nerve , tibial nerve , ulnar nerve conduction velocity and the total efficiency of the two groups of patients after treatment.Results After treat-ment, the patient study group median nerve speed was (45.37±3.43) m/s, the ulnar nerve was(44.56±2.83)m/s, the tibial nerve was (45.37±3.43)m/s, while the control group median nerve was (43.45±3.18) m/s, the ulnar nerve was (40.21±2.16)m/s, the tibial nerve is (41.23±3.19)m/s, comparing the two groups, the study group of patients with median nerve, ulnar nerve, tibial nerve con-duction velocity was significantly better than the control group, the difference was statistically significant ( P<0.05); the patient study group median nerve speed was, tibial nerve,ulnar nerve conduction velocity was significantly better than the control group, the difference was statistically significant (P<0.05); after treatment total effective rate of the study group was 83.9% the control group was 41.7% ,the difference was statistically significant (χ2=7.6592, P=0.0056). Conclusion Lipoic acid can do well in the therapy of diabetic peripheral neuropathy,so it is worthy of promotion.
