CAJ | 학술논문

目的：探讨动态血糖监测系统(CGMS)对妊娠期糖尿病(GDM)患者妊娠结局的影响。方法选择2011年1月~2012年12月在深圳市龙岗区人民医院就诊的GDM患者60例，分为A组和B组，每组各30例。 A组患者给予24 h动态血糖监测，B组行常规末梢血糖检查，未予动态血糖监测。统计并比较：①两组孕妇妊娠高血压综合征、早产、宫内感染、羊水过多、胎膜早破、剖宫产等围生期并发症发生率；②两组新生儿高胆红素血症、低血糖、围生儿死亡、新生儿窒息、巨大儿的发生率及新生儿体重及新生儿胎龄情况。结果①B组妊娠高血压综合征[13.33%(4/30)]、早产[6.67%(2/30)]、宫内感染[6.67%(2/30)]、羊水过多[6.67%(2/30)]、胎膜早破[10.00%(3/30)]、剖宫产[53.33%(16/30)]发生率明显高于A组[6.67%(2/30)、3.33%(1/30)、0.00%(0/30)、0.00%(0/30)、3.33%(1/30)、40.00%(12/30)]，差异均有统计学意义(P<0.05)。于两组围生儿并发症比较，B组高胆红素血症[13.33%(4/30)]、低血糖[6.67%(2/30)]、新生儿体重[(3345±512)g]、新生儿窒息[6.67%(2/30)]、巨大儿[6.67%(2/30)]等项均明显高于A组[6.67%(2/30)、0.00%(0/30)、(3045±460)g、0.00%(0/30)、0.00%(0/30)]，差异均有统计学意义(P<0.05)。结论CGMS能为需要治疗的GDM患者提供早期的动态血糖监测，为后续的治疗提供更准确的血糖依据，是有效降低母婴并发症和合并症的监测方法之一。
목적：탐토동태혈당감측계통(CGMS)대임신기당뇨병(GDM)환자임신결국적영향。방법선택2011년1월~2012년12월재심수시룡강구인민의원취진적GDM환자60례，분위A조화B조，매조각30례。 A조환자급여24 h동태혈당감측，B조행상규말소혈당검사，미여동태혈당감측。통계병비교：①량조잉부임신고혈압종합정、조산、궁내감염、양수과다、태막조파、부궁산등위생기병발증발생솔；②량조신생인고담홍소혈증、저혈당、위생인사망、신생인질식、거대인적발생솔급신생인체중급신생인태령정황。결과①B조임신고혈압종합정[13.33%(4/30)]、조산[6.67%(2/30)]、궁내감염[6.67%(2/30)]、양수과다[6.67%(2/30)]、태막조파[10.00%(3/30)]、부궁산[53.33%(16/30)]발생솔명현고우A조[6.67%(2/30)、3.33%(1/30)、0.00%(0/30)、0.00%(0/30)、3.33%(1/30)、40.00%(12/30)]，차이균유통계학의의(P<0.05)。우량조위생인병발증비교，B조고담홍소혈증[13.33%(4/30)]、저혈당[6.67%(2/30)]、신생인체중[(3345±512)g]、신생인질식[6.67%(2/30)]、거대인[6.67%(2/30)]등항균명현고우A조[6.67%(2/30)、0.00%(0/30)、(3045±460)g、0.00%(0/30)、0.00%(0/30)]，차이균유통계학의의(P<0.05)。결론CGMS능위수요치료적GDM환자제공조기적동태혈당감측，위후속적치료제공경준학적혈당의거，시유효강저모영병발증화합병증적감측방법지일。
Objective To investigate the influence of pregnancy outcome in GDM patients by continuous glucose moni-toring system (CGMS). Methods 60 patients with GDM in Longgang District People's Hospital of Shenzhen City from January 2011 to December 2012 were selected and divided into group A and group B with 30 cases in each group. The group A was treated with continuous glucose monitoring for 24 h, group B was treated with normal peripheral blood sugar checking without continuous glucose monitoring. The indexes were observed and compared:①the occurrence rate of perinatal complications of pregnancy induced hypertension, premature birth, intrauterine infection, polyhydramnios, premature rupture of fetal membranes, cesarean delivery in pregnant women of the two groups; ②the occurrence rate of hyperbilirubinemia, hypoglycemia, perinatal death, asphyxia neonatorum, fetal macrosomia, weight and gestational age in newborn of the two groups. Results ①The occurrence rate of pregnancy induce d hypertension, pregnancy induced hypertension, intrauterine infection, polyhydramnios, premature rupture of fetal membranes, caesarean section in group B [13.33% (4/30), 6.67% (2/30), 6.67% (2/30), 6.67% (2/30), 10.00% (3/30), 53.33% (16/30)] were all higher than those in group A [6.67% (2/30), 3.33% (1/30), 0.00%(0/30), 0.00% (0/30), 3.33% (1/30), 40.00%(12/30)], the differences were statistically significant (P< 0.05).②The hyperbilirubinemia, hypoglycemia, newborn weight, neonatal asphyxia, fetal macrosomia in group B [13.33%(4/30), 6.67%(2/30), (3345±512) g, 6.67%(2/30), 6.67%(2/30)] were all higher than those in group A [6.67% (2/30), 0.00% (0/30), (3045±460) g, 0.00% (0/30), 0.00% (0/30)], the differences were statistically significant (P< 0.05). Conclusion It is able for CGMS to provide the early dynamic blood sugar monitoring for GDM patients, it also can provide more accurate blood sugar basis for the subsequent treat-ment, it is one of the methods to reduce the maternal complications and complications effectively.