中国医药导报
中國醫藥導報
중국의약도보
CHINA MEDICAL HERALD
2014年
16期
91-93
,共3页
微柱凝胶技术%不规则抗体筛查%安全输血%输血反应
微柱凝膠技術%不規則抗體篩查%安全輸血%輸血反應
미주응효기술%불규칙항체사사%안전수혈%수혈반응
Microtube gel technology%Irregular antibody screening%Safe transfusion blood%Blood transfusion reaction
目的：分析微柱凝胶技术对输血患者进行血型不规则抗体的筛查情况及临床应用。方法对2010年1月~2013年12月于桂林医学院附属医院输血患者29208例进行不规则抗体检测，统计分析阳性结果，鉴定阳性抗体的特异性。结果29208例患者中，检出不规则抗体阳性者90例，阳性率为0.31%。特异性抗体以Rh血型系统居多，抗-D抗体占2.22%、抗-E抗体占21.11%、抗-Ec抗体占11.11%；MNSs系统抗-Mur抗体11例(12.22%)、抗-M抗体7例(7.78%)；Lewis系统抗-Lea抗体占8.89%；冷抗体占7.78%。非特异性抗体占13.33%。结论输血前对患者血液进行血型不规则抗体筛查并鉴定其特异性，输注不含相应抗原的血液，避免溶血性输血反应的发生，对确保输血安全有效有重要的临床意义。
目的：分析微柱凝膠技術對輸血患者進行血型不規則抗體的篩查情況及臨床應用。方法對2010年1月~2013年12月于桂林醫學院附屬醫院輸血患者29208例進行不規則抗體檢測，統計分析暘性結果，鑒定暘性抗體的特異性。結果29208例患者中，檢齣不規則抗體暘性者90例，暘性率為0.31%。特異性抗體以Rh血型繫統居多，抗-D抗體佔2.22%、抗-E抗體佔21.11%、抗-Ec抗體佔11.11%；MNSs繫統抗-Mur抗體11例(12.22%)、抗-M抗體7例(7.78%)；Lewis繫統抗-Lea抗體佔8.89%；冷抗體佔7.78%。非特異性抗體佔13.33%。結論輸血前對患者血液進行血型不規則抗體篩查併鑒定其特異性，輸註不含相應抗原的血液，避免溶血性輸血反應的髮生，對確保輸血安全有效有重要的臨床意義。
목적：분석미주응효기술대수혈환자진행혈형불규칙항체적사사정황급림상응용。방법대2010년1월~2013년12월우계림의학원부속의원수혈환자29208례진행불규칙항체검측，통계분석양성결과，감정양성항체적특이성。결과29208례환자중，검출불규칙항체양성자90례，양성솔위0.31%。특이성항체이Rh혈형계통거다，항-D항체점2.22%、항-E항체점21.11%、항-Ec항체점11.11%；MNSs계통항-Mur항체11례(12.22%)、항-M항체7례(7.78%)；Lewis계통항-Lea항체점8.89%；랭항체점7.78%。비특이성항체점13.33%。결론수혈전대환자혈액진행혈형불규칙항체사사병감정기특이성，수주불함상응항원적혈액，피면용혈성수혈반응적발생，대학보수혈안전유효유중요적림상의의。
Objective To analyze the situation and clinical application of microtube gel technology (MGT) in the irreg-ular antibody screening of patients before blood transfusion. Methods 29 208 patients from January 2010 to December 2013 in Affiliated Hospital of Guilin Medical University were screened for irregular antibody. The results were statisti-cal analyzed to identify the specificity of positive antibody. Results Among 29 208 patients, there were 90 cases with irregular antibody, the positive rate was 0.31%. Rh blood type system accounted for the most part of the specific anti-bodies: 2.22% for anti-D antibody, 21.11% of anti-E antibody and 11.11% of anti-Ec antibody. 11 cases of Anti-Mur of MNSs system accounted for 12.22% of the total and 7 cases of anti-M antibody accounted for 7.78%. 8.89% was for Anti-Lea antibody in Lewis system and 7.78% for cold antibody. And the non-specific antibodies accounted for 13.33%. Conclusion Irregular antibody should be screened and its specificity should also be identified before transfu-sion. To transfuse the blood without the corresponding antibodies can prevent transfusional hemolytic reaction, which is of great significance in safe and effective transfusion in clinical work.
